|Official Full Name||septin 12|
|Background||This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene.|
|Synonyms||SEPT12; septin 12; septin-12; FLJ25410; SEPT12; SEP12_HUMAN; Septin-12; Septin12|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
sept12 involved in several pathways and played different roles in them. We selected most pathways sept12 participated on our site, such as Bacterial invasion of epithelial cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with sept12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Bacterial invasion of epithelial cells||CDH1; SHC1; SEPT12; ELMO2; ARPC2; SEPT2; SHC2; CBL; CAV2; GAB1|
sept12 has several biochemical functions, for example, GDP binding, GTP binding, phosphatidylinositol binding. Some of the functions are cooperated with other proteins, some of the functions could acted by sept12 itself. We selected most functions sept12 had, and list some proteins which have the same functions with sept12. You can find most of the proteins on our site.
|GDP binding||RAB2A; RAB31; GEM; EIF2B1; PIGC; RAB40C; RALB; RAB22A; RAN; RAB5C|
|GTP binding||ASCL1B; SEPT5A; RASL10A; RAC2; TPX2; TUBA8L3; GTPBP10; ARL4CA; GMPPB; RAB42|
|phosphatidylinositol binding||PIK3C2A; RPS6KC1; SH3PXD2A; ING2; SNX10B; SNX17; SNX18B; PASK; TNFAIP8L3; SNX9B|
|protein binding||SLIT2; TMEM140; TRIM10; ADAM17; TRIM35; NEK6; OSBP2; CREB5; VEGFC; TAL1|
|protein homodimerization activity||NRBP1; HELT; PAFAH1B2; DMRT3; ZFP365; BAX; SUMF1; CD200; BIRC5; CCL5|
sept12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with sept12 here. Most of them are supplied by our site. Hope this information will be useful for your research of sept12.
SEPT6; SPAG4; SEPT1; LMNB1; SEPT4; OBSL1; PRM2; PCM1; NDC1