"KLRK1" Related Products

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Recombinant Human killer cell lectin-like receptor subfamily K, member 1, His-tagged

Cat.No.: KLRK1-379H
Product Overview: KLRK1, 73-216 aa, Human, His tag, E.coli
Description: KLRK1 is an activating receptor that has recently generated considerable interest. The most intriguing of these are a pair of closely related proteins called MICA and MICB. These are cell-surface molecules distantly related to MHC class I proteins, and the genes possess elements of heat shock promoters. MICA and MICB, therefore, are expressed during cell stress and are up-regulated in tumor cells and during viral infections. This receptor-ligand combination may play a critical role in the immune response to a variety of pathologies. Recombinant human KLRK1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
Source: E.coli
Species: Human
Tag: His-tag
Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.4M Urea
Molecular Mass: 19.2 kDa(168aa)
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMIWSAVF LNSLFNQEVQ IPLTESYCGP CPKNWICYKN NCYQFFDESK NWYESQASCM SQNASLLKVY SKEDQDLLKL VKSYHWMGLV HIPTNGSWQW EDGSILSPNL LTIIEMQKGD CALYASSFKG YIENCSTPNT YICMQRTV
Purity: >90% by SDS - PAGE
Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration: 0.5 mg/ml (determined by Bradford assay)
Gene Name: KLRK1 killer cell lectin-like receptor subfamily K, member 1 [ Homo sapiens ]
Official Symbol: KLRK1
Synonyms: KLRK1; killer cell lectin-like receptor subfamily K, member 1; D12S2489E, DNA segment on chromosome 12 (unique) 2489 expressed sequence; NKG2-D type II integral membrane protein; CD314; KLR; NKG2 D; NKG2D; NK cell receptor D; NKG2-D-activating NK receptor; NKG2-D; D12S2489E; FLJ17759; FLJ75772;
Gene ID: 22914
mRNA Refseq: NM_007360
Protein Refseq: NP_031386
MIM: 611817
UniProt ID: P26718
Chromosome Location: 12p13.2-p12.3
Pathway: Adaptive Immune System, organism-specific biosystem; Immune System, organism-specific biosystem; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, organism-specific biosystem; Malaria, organism-specific biosystem; Malaria, conserved biosystem; Natural killer cell mediated cytotoxicity, organism-specific biosystem; Natural killer cell mediated cytotoxicity, conserved biosystem;

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