Cat.No.: |
ICOS-1533H |
Product Overview: |
The extracellular domain of human CD278 [ICOS] (NP_036224.1) (Glu21-Leu139) is fused to the N-terminus of the Fc region of human IgG1 was expressed in CHO cell. |
Description: |
The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimersand plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation. |
Source: |
CHO cells |
Species: |
Human |
Tag: |
HIgG1 Fc-tagged |
Form: |
Lyophilized from 0.2μm-filtered solution in PBS. |
Bio-activity: |
Measured by its ability to inhibit human T cell proliferation induced by rhB7-H2/Fc Chimera in the presence of anti-CD3. |
Molecular Mass: |
40 KDa (monomer) |
AA Sequence: |
Glu21-Leu139 |
Endotoxin: |
<0.06 eu/μg as determined by lal>0.06> |
Purity: |
>98%, by SDS-PAGE under reducing conditions. |
Stability: |
Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
Reconstitution: |
Reconstitute at 100μg/ml in sterile PBS. |
Warning: |
Avoid freeze/thaw cycles. |