Recombinant Human ICOS Protein, Fc-tagged

• Cat.No.: ICOS-672H
• Product Overview: Recombinant human ICOS protein with Fc tag was expressed in HEK293.

Specification

• Description: The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation.
• Source: HEK293
• Species: Human
• Tag: Fc
• Form: Lyophilized
• Molecular Mass: 40.4 kDa
• Protein length: 199
• AA Sequence: MKSGLWYFFLFCLRIKVLTGEINGS ANYEMFIFHNGGVQILCKYPDIVQQ FKMQLLKGGQILCDLTKTKGSGNTV SIKSLKFCHSQLSNNSVSFFLYNLD HSHANYYFCNLSIFDPPPFKVTLTG GYLHIYESQLCCQLKFWLPIGCAAF VVVCILGCILICWLTKKKYSSSVHD PNGEYMFMRAVNTAKKSRLTDVTL
• Purity: > 98%
• Applications: WB; ELISA; FACS; FC
• Stability: This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use.
• Storage: At -20 centigrade.
• Concentration: 1 mg/mL
• Storage Buffer: PBS (pH 7.4-7.5). Sterile-filtered colorless solution.
• Reconstitution: Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.

Gene Information

• Gene Name: ICOS inducible T-cell co-stimulator [ Homo sapiens (human) ]
• Official Symbol: ICOS
• Synonyms: ICOS; inducible T-cell co-stimulator; inducible T-cell costimulator; activation inducible lymphocyte immunomediatory molecule; AILIM; CD278; inducible costimulator; activation-inducible lymphocyte immunomediatory molecule; CVID1; MGC39850
• Gene ID: 29851
• mRNA Refseq: NM_012092
• Protein Refseq: NP_036224
• MIM: 604558
• UniProt ID: Q9Y6W8