Recombinant Human FYN
Cat.No. : | FYN-28958TH |
Product Overview : | Recombinant full length Fyn protein with an N-terminal tag, expressed by baculovirus in Sf9 insect cells. MW ~85kDa. |
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Description : | This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist. |
Tissue specificity : | Isoform 1 is highly expressed in the brain. Isoform 2 is expressed in cells of hemopoietic lineages, especially T lymphocytes. |
Biological activity : | Specific activity: 166nmol/min/mg. |
Form : | Liquid |
Storage buffer : | Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5 |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequence Similarities : | Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.Contains 1 protein kinase domain.Contains 1 SH2 domain.Contains 1 SH3 domain. |
Gene Name : | FYN FYN oncogene related to SRC, FGR, YES [ Homo sapiens ] |
Official Symbol : | FYN |
Synonyms : | FYN; FYN oncogene related to SRC, FGR, YES; tyrosine-protein kinase Fyn; MGC45350; SLK; SYN; |
Gene ID : | 2534 |
mRNA Refseq : | NM_002037 |
Protein Refseq : | NP_002028 |
MIM : | 137025 |
Uniprot ID : | P06241 |
Chromosome Location : | 6q21 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Alpha-synuclein signaling, organism-specific biosystem; Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem; |
Function : | ATP binding; ephrin receptor binding; glycoprotein binding; metal ion binding; non-membrane spanning protein tyrosine kinase activity; |
Products Types
◆ Recombinant Protein | ||
FYN-420H | Recombinant Human FYN Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
Fyn-3119M | Recombinant Mouse Fyn Protein, Myc/DDK-tagged | +Inquiry |
FYN-4585H | Active Recombinant Human FYN Protein, GST/His-tagged | +Inquiry |
FYN-4586H | Recombinant Human FYN Protein, GST-tagged | +Inquiry |
FYN-3407M | Recombinant Mouse FYN Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
FYN-6091HCL | Recombinant Human FYN 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionFYN protein is involved in regulating synaptic plasticity, which plays a crucial role in learning and memory.
Yes, FYN protein is also associated with cancer, particularly in regulating cell proliferation and survival.
Targeting FYN protein is being studied for its potential applications in the treatment of autoimmune diseases to modulate immune responses.
Some targeted therapies aimed at inhibiting FYN protein have been explored for specific types of cancer.
Yes, FYN protein levels can be measured in clinical settings through various laboratory techniques.
Customer Reviews (3)
Write a reviewthe manufacturer fosters scientific collaboration and knowledge sharing among researchers.
They can offer insights into interpreting results and assist in identifying trends or patterns that may be relevant to the specific research question.
This guarantees a continuous and uninterrupted availability of the protein for researchers, eliminating concerns about potential shortages or delays.
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