"FYN" Related Products

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Recombinant Human FYN

Cat.No.: FYN-28958TH
Product Overview: Recombinant full length Fyn protein with an N-terminal tag, expressed by baculovirus in Sf9 insect cells. MW ~85kDa.
Description: This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist.
Tissue specificity: Isoform 1 is highly expressed in the brain. Isoform 2 is expressed in cells of hemopoietic lineages, especially T lymphocytes.
Biological activity: Specific activity: 166nmol/min/mg.
Form: Liquid
Storage buffer: Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities: Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.Contains 1 protein kinase domain.Contains 1 SH2 domain.Contains 1 SH3 domain.
Gene Name: FYN FYN oncogene related to SRC, FGR, YES [ Homo sapiens ]
Official Symbol: FYN
Synonyms: FYN; FYN oncogene related to SRC, FGR, YES; tyrosine-protein kinase Fyn; MGC45350; SLK; SYN;
Gene ID: 2534
mRNA Refseq: NM_002037
Protein Refseq: NP_002028
MIM: 137025
Uniprot ID: P06241
Chromosome Location: 6q21
Pathway: Adaptive Immune System, organism-specific biosystem; Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Alpha-synuclein signaling, organism-specific biosystem; Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem;
Function: ATP binding; ephrin receptor binding; glycoprotein binding; metal ion binding; non-membrane spanning protein tyrosine kinase activity;

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