FYN

  • Official Full Name

    FYN oncogene related to SRC, FGR, YES

  • Overview

    This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase;that has been implicated in the control of cell growth. The protein associates with the p85 subunit of;phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants;encoding distinct isoforms exist.
  • Synonyms

    FYN; FYN oncogene related to SRC, FGR, YES; tyrosine-protein kinase Fyn; MGC45350; SLK; SYN; src-like kinase; proto-oncogene Syn; c-syn protooncogene; proto-oncogene c-Fyn; src/yes-related novel; tyrosine kinase p59fyn(T); OKT3-induced calcium influx regu;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Insect (sf21)
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Sf9 Insect Cell
  • Wheat Germ
  • C
  • Myc
  • DDK
  • Flag
  • GST
  • GST|His
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FYN-322H Recombinant Human FYN, GST-tagged, Active Sf9 Insect Cell GST
Human FYN-217H Recombinant Human FYN Oncogene Related To SRC, FGR, YES E.coli N/A
Human FYN-50H Recombinant Human FYN protein, Flag-tagged, Biotinylated Insect Cell Flag
Human FYN-28958TH Recombinant Human FYN N/A
Human FYN-2128H Recombinant Human FYN Oncogene Related To SRC, FGR, YES, His-tagged Insect Cell His
Human FYN-2410H Recombinant Human FYN, GST-tagged E.coli GST
Human FYN-6091HCL Recombinant Human FYN 293 Cell Lysate HEK293 N/A
Human FYN-1388H Recombinant Human FYN Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human FYN-4585H Active Recombinant Human FYN Protein, GST/His-tagged Insect Cell GST/His
Human FYN-4586H Recombinant Human FYN Protein, GST-tagged Wheat Germ GST
Human FYN-420H Recombinant Human FYN Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
Human FYN-5284HF Recombinant Full Length Human FYN Protein, GST-tagged In Vitro Cell Free System GST
Human FYN-949H Recombinant Human FYN Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human FYN-1766H Recombinant Human FYN protein, His & T7-tagged E.coli His/T7
Human FYN-3213H Recombinant Human FYN Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human FYN-0397H Recombinant Human FYN protein, His-tagged E.coli His
Human FYN-5832HF Active Recombinant Full Length Human FYN Protein, DDK-tagged, Biotinylated Insect (sf21) DDK
Human FYN-8109HF Active Recombinant Full Length Human FYN Protein, GST-tagged Insect (sf21) GST
Human FYN-7192HF Active Recombinant Full Length Human FYN Protein, GST-tagged Insect (sf21) GST
Human FYN-822HFL Active Recombinant Full Length Human FYN Protein, C-Flag-tagged Mammalian cells Flag
Human FYN-949H-B Recombinant Human FYN Protein Pre-coupled Magnetic Beads HEK293
Mouse FYN-6112M Recombinant Mouse FYN Protein Mammalian Cell His
Mouse Fyn-3119M Recombinant Mouse Fyn Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse FYN-3407M Recombinant Mouse FYN Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse FYN-3407M-B Recombinant Mouse FYN Protein Pre-coupled Magnetic Beads HEK293
Rat FYN-2427R Recombinant Rat FYN Protein Mammalian Cell His
Rat FYN-2083R-B Recombinant Rat FYN Protein Pre-coupled Magnetic Beads HEK293
Rat FYN-2083R Recombinant Rat FYN Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Chicken FYN-6901C Recombinant Chicken FYN Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • FYN Related Articles
  • FYN Related Gene Family
  • FYN Related Research Area

FYN involved in several pathways and played different roles in them. We selected most pathways FYN participated on our site, such as Sphingolipid signaling pathway, Phospholipase D signaling pathway, Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with FYN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Sphingolipid signaling pathwayMAPK13;MAP3K5;ASAH2;SPHK1;DEGS2;PLCB1;PLCB2;PLCB3;PPP2R2D
Phospholipase D signaling pathwayAKT2;PLA2G4C;GNA12;PLD2;PLCB3;AVP;IL-8;PPAP2A;GRM1
Axon guidanceRNF8;DUSP9;PEBP1;UNC5D;NRG3;UNC5C;RHOA;SPRED2;ABL1
Osteoclast differentiationMAP3K7;FCGR2A;LILRB1;TYK2;OSCAR;FCGR4;SOCS3;MAPK9;TNFRSF11B
Focal adhesionSTYK1;RAC1;RAC3B;ROCK2A;MYL9B;PIK3CB;COL2A1;COL27A1B;PTK6
Adherens junctionFYNB;CDC42L;RAC2;ACTG1;ACTB;ACTN4;CSNK2A2;CREBBP;SMAD4
Platelet activationVAMP8;GNAI1;RAP1A;ITGB1;MAPK11;PIK3R1;GNAQ;PIK3R3;FGG
Natural killer cell mediated cytotoxicityPRKCB;PIK3CD;HCST;ARAF;IFNA12;IFNA1;LAT;ICAM2;MAPK1
T cell receptor signaling pathwayCBLB;PIK3R2;NCK2;TEC;MAPK13;PPP3CB;PAK1;PIK3CB;CD4
Fc epsilon RI signaling pathwayLAT;VAV2;PIK3R2;PLA2G4A;PLA2G4B;MAP2K4;PDPK1;MAPK13;PLA2G4C
Cholinergic synapseACHE;GNAI2;GNG7;ITPR1;GNG5;MAP2K1;CAMK2B;PIK3CA;GNG2
Prion diseasesELK1;C1QA;NCAM2;HSPA1A;HSPA5;C7;PRNP;C5;C9
Pathogenic Escherichia coli infectionRHOA;TUBA3C;WAS;CDC42;WASL;TUBB6;CD14;FYN;TUBA3D
MeaslesPIK3CD;NFKBIA;OAS2;IFNG;TRAF6;PIK3R1;PIK3CB;EIF2AK3;CD3G
Viral myocarditisCasp3;CAV1;HLA-DOA;HLA-DQB1;ACTB;ACTG1;CCND1;H2-AB1;LAMA2

FYN has several biochemical functions, for example, ATP binding, CD4 receptor binding, CD8 receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FYN itself. We selected most functions FYN had, and list some proteins which have the same functions with FYN. You can find most of the proteins on our site.

Function Related Protein
ATP bindingGC2;PCCA;CAMK1G;MKNK1;HSP70L;FASTK;ITPKB;PAPOLB;MADD
CD4 receptor bindingPLSCR1;SPG21;FYN;PLSCR4;LCK
CD8 receptor bindingFYN;LCK
G-protein coupled receptor bindingGNA15.1;FYN;STUB1;QRFP;SFTPB;UTS2D;PSAPL1;GNA13B;SAA1
T cell receptor bindingCD3E;CD3G;FYN;HLA-A;EPS8L1;DOCK2;CD1d1;H2-Q10
ephrin receptor bindingEFNA1;EFNA5;SHC1;EFNA2;SDCBP;PTPN1;EPHA7;GRB2;CDK5R1
glycoprotein bindingF7;PTBP3;FLNA;VLDLR;CNTN2;LRRK2;FGFR1;BMPR1A;CD4
growth factor receptor bindingAPP;FYN;SRC;SLC9A3R1
ion channel bindingYWHAH;ASPH;DIAP1;FYN;FAM115C;CAV1;TRPC1;RANGRF;FHL1
metal ion bindingITGA4;CHD4A;PDE4C;TRIM35-24;HELZ;AOC1;MYOC;LACTB2;RIMKLA
non-membrane spanning protein tyrosine kinase activityLCK;ZAP70;TNK1;SRMS;YES1;DYRK1A;CSK;EIF2AK2;JAK2A
peptide hormone receptor bindingPTHLH;PTPN11;NPPC;LEP;PTH;FYN;RUNDC3A;PTHLHA;JAK2
phosphatidylinositol 3-kinase bindingINSRA;INSRR;CALM2;CALM1;CORO1A;PDGFRB;TYRO3;DAB1;IRS4
protein bindingNSFL1C;TRMT12;RFWD2;PLAA;ERC1;DNM3;NR2C1;SERINC1;PICALM
protein tyrosine kinase activityMAP2K2;KDRL;EK1;KIT;MAP3K9;CLK3;CSF1RA;MAP2K3;FGFR3
tubulin bindingSTMN1;VBP1;CENPJ;EML2;BRCA1;STMN3;TBCC;TTLL6;TPPP3

FYN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FYN here. Most of them are supplied by our site. Hope this information will be useful for your research of FYN.

FYB; CBL; PRKCD; KHDRBS1

Nisbet, RM; Polanco, JC; et al. Tau aggregation and its interplay with amyloid-beta. ACTA NEUROPATHOLOGICA 129:207-220(2015).
Gujral, TS; Chan, M; et al. A Noncanonical Frizzled2 Pathway Regulates Epithelial-Mesenchymal Transition and Metastasis. CELL 159:844-856(2014).
TGF
  • Q&As
  • Reviews

Q&As (5)

Ask a question
How does FYN protein affect synaptic plasticity? 08/13/2020

FYN protein is involved in regulating synaptic plasticity, which plays a crucial role in learning and memory.

Is FYN protein involved in cancer biology? 01/21/2020

Yes, FYN protein is also associated with cancer, particularly in regulating cell proliferation and survival.

Can targeting FYN protein have applications in autoimmune diseases? 08/16/2019

Targeting FYN protein is being studied for its potential applications in the treatment of autoimmune diseases to modulate immune responses.

Are there any targeted therapies that inhibit FYN protein for cancer treatment? 11/13/2018

Some targeted therapies aimed at inhibiting FYN protein have been explored for specific types of cancer.

Can FYN protein levels be measured in clinical settings? 01/20/2018

Yes, FYN protein levels can be measured in clinical settings through various laboratory techniques.

Customer Reviews (3)

Write a review
Reviews
07/27/2020

    the manufacturer fosters scientific collaboration and knowledge sharing among researchers.

    02/27/2020

      They can offer insights into interpreting results and assist in identifying trends or patterns that may be relevant to the specific research question.

      12/23/2019

        This guarantees a continuous and uninterrupted availability of the protein for researchers, eliminating concerns about potential shortages or delays.

        Ask a Question for All FYN Products

        Required fields are marked with *

        My Review for All FYN Products

        Required fields are marked with *

        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends