"Ebi3" Related Products

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Recombinant Mouse Epstein-Barr Virus Induced Gene 3

Cat. No.: Ebi3-1317M
Product Overview: Recombinant Mouse EBI produced inE.coliis a non-glycosylated polypeptide chain consisting of 207 amino acids with a molecular weight of 23 kDa.
Description: Epstein-Barr Virus Induced Gene-3 (EBI-3), is a secreted glycoprotein belonging to the hematopoietin receptor family and related to the p40 subunit of IL-12. It was identified by its induced expression in B-lymphocytes in response to Epstein-Barr virus infection. EBI-3 forms heterodimers with p28 to form IL-27 and with p35 to form IL-35. Both IL-27 and IL-35 have anti-inflammatory and regulatory activity.
Source: E.coli.
AA Sequence: MALVALSQPR VQCHASRYPV AVDCSWTPLQ APNSTRSTSF IATYRLGVAT QQQSQPCLQR SPQASRCTIP DVHLFSTVPY MLNVTAVHPG GASSSLLAFV AERIIKPDPP EGVRLRTAGQ RLQVLWHPPA SWPFPDIFSL KYRLRYRRRG ASHFRQVGPI EATTFTLRNS KPHAKYCIQV SAQDLTDYGK PSDWSLPGQV ESAPHKP
Formulation: Lyophilized from 10 mM NaCitrate, pH 3.0.
Purity: Greater than 90% as determined by: (1) Reducing and non-reducing SDS-PAGE. (2) Analytical HPLC.
Biological Activity: Assay data for mouse recombinant EBI-3 is based upon qualitative binding to anti-EBI-3 antibody.
Endotoxin: Endotoxin level as measured by LAL is <0.01ng/ug or <0.1EU/ug.
Protein Content: Determined by: (1) UV spectroscopy at 280 nm. (2) Quantitation on SDS-PAGE against a known standard.
Reconstitution: It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 - 0.5 mg /ml, which can be further diluted into other aqueous solutions.
Stability: Lyophilized product is very stable at -20°C. Reconstituted material should be aliquoted and frozen at -20°C. It is recommended to add a carrier protein (0.1% HSA or BSA) for long term storage.
Gene Name: Ebi3 Epstein-Barr virus induced gene 3 [ Mus musculus ]
Synonyms: Ebi3; Epstein-Barr virus induced gene 3; EBI-3; IL-27; Epstein-Barr virus induced 3
Gene ID: 50498
mRNA Refseq: NM_015766
Protein Refseq: NP_056581
UniProt ID: O35228
Chromosome Location: 17 33.0 cM
Function: cytokine activity; cytokine receptor activity; interleukin-27 receptor binding; protein binding

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