EBI3

  • Official Full Name

    Epstein-Barr virus induced gene 3

  • Overview

    This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form interleukin 27 (IL-27). IL-27 regulates T cell and inflammatory responses, in part by activating the Jak/STAT pathway of CD4+ T cells.
  • Synonyms

    EBI3; Epstein-Barr virus induced gene 3; interleukin-27 subunit beta; IL-27B; IL-27 subunit beta; epstein-Barr virus-induced gene 3 protein homolog; EBI-3; IL-27;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Macaque
  • Mouse
  • Zebrafish
  • CHO
  • E.coli
  • HEK293
  • Human
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • Yeast
  • C
  • His
  • Fc
  • GST
  • His (Fc)
  • Avi
  • His(C
  • ter)
  • His|T7
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human EBI3-504H Active Recombinant Human Epstein-Barr Virus Induced 3 E.coli N/A
Human EBI3-287H Recombinant Human EBI3, Fc tagged Human Cell Fc
Human EBI3-45H Recombinant Human EBI3 Yeast N/A
Human EBI3-27965TH Recombinant Human EBI3, Fc-tagged HEK293 Fc
Human EBI3-4135H Recombinant Human Epstein-Barr Virus Induced 3, His-tagged Human His
Human EBI3-8522H Recombinant Human EBI3, His tagged CHO His
Human EBI3-27028TH Recombinant Human EBI3, His-tagged E.coli His
Human EBI3-3024H Recombinant Human EBI3 Protein E.coli N/A
Human EBI3-2233H Recombinant Human EBI3 Protein, GST-tagged Wheat Germ GST
Human EBI3-240HCL Recombinant Human EBI3 lysate HEK293 N/A
Human EBI3-59H Recombinant Active Human EBI3 Protein, His-tagged(C-ter) E.coli His(C-ter)
Human Ebi3-4224H Recombinant Human Ebi3 protein, His-GST-tagged E.coli His/GST
Human EBI3-71H Active Recombinant Human EBI3 subunit (IL-27/IL-35) Protein E.coli
Human EBI3-975HF Recombinant Full Length Human EBI3 Protein, GST-tagged In Vitro Cell Free System GST
Human EBI3-72H Active Recombinant Human IL-35 Heterodimer Protein HEK293
Human EBI3-1674H Recombinant Human EBI3 Protein (Arg21-Lys229), His tagged E.coli His
Human EBI3-06H Active Recombinant Human EBI3 Protein (Arg21-Lys229), C-His tagged, Animal-free, Carrier-free E.coli C-His
Mouse Ebi3&Il27-952M Active Recombinant Mouse Ebi3&Il27 protein, His-tagged HEK293 His
Mouse Ebi3-7931M Recombinant Mouse Ebi3 protein, His & T7-tagged E.coli His/T7
Mouse EBI3-4958M Recombinant Mouse EBI3 Protein Mammalian Cell His
Mouse Ebi3-8702M Recombinant Mouse Ebi3, His tagged Human Cell His
Mouse Ebi3-1317M Recombinant Mouse Epstein-Barr Virus Induced Gene 3 E.coli N/A
Mouse EBI3-2616M Recombinant Mouse EBI3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Ebi3-73M Active Recombinant Mouse EBI3 Subunit (IL-27/IL-35) Protein E.coli
Mouse Ebi3-60M Recombinant Active Mouse EBI3 Protein, His-tagged(C-ter) E.coli His(C-ter)
Mouse EBI3-2616M-B Recombinant Mouse EBI3 Protein Pre-coupled Magnetic Beads HEK293
Mouse Ebi3-239M Active Recombinant Mouse Ebi3 Protein (Ala23-Pro228), C-His tagged, Animal-free, Carrier-free E.coli C-His
Macaque EBI3-70M Active Recombinant Macaque EBI3 subunit (IL-27/IL-35) Protein E.coli
Zebrafish EBI3-6307Z Recombinant Zebrafish EBI3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • EBI3 Related Articles
  • EBI3 Related Research Area

EBI3 involved in several pathways and played different roles in them. We selected most pathways EBI3 participated on our site, such as mRNA processing, which may be useful for your reference. Also, other proteins which involved in the same pathway with EBI3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
mRNA processingDDX20;EBI3;LOC100862398;SFSWAP;RNASET2B;DHX15;D19BWG1357E;RAVER1;PRPF4B

EBI3 has several biochemical functions, for example, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EBI3 itself. We selected most functions EBI3 had, and list some proteins which have the same functions with EBI3. You can find most of the proteins on our site.

Function Related Protein
poly(A) RNA bindingH1FX;NOVA1;RPL14;SOSTDC1B;LBR;NOL12;MTHFSD;MRPL15;EIF4A1

EBI3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EBI3 here. Most of them are supplied by our site. Hope this information will be useful for your research of EBI3.

SMAD3; MDFI

Mitani, A; Niedbala, W; et al. Increased Expression of Interleukin (IL)-35 and IL-17, But Not IL-27, in Gingival Tissues With Chronic Periodontitis. JOURNAL OF PERIODONTOLOGY 86:301-309(2015).
Singh, K; Hjort, M; et al. Concomitant analysis of Helios and Neuropilin-1 as a marker to detect thymic derived regulatory T cells in naive mice. SCIENTIFIC REPORTS 5:-(2015).
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