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Recombinant Active Human EBI3 Protein, His-tagged(C-ter)

Cat.No. : EBI3-59H
Product Overview : Recombinant Active Human EBI3 Protein with His tag (C-ter) was expressed in E. coli.
  • Specification
  • Gene Information
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Description : This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form interleukin 27 (IL-27). IL-27 regulates T cell and inflammatory responses, in part by activating the Jak/STAT pathway of CD4+ T cells. [provided by RefSeq, Sep 2008]
Source : E. coli
Species : Human
Tag : His(C-ter)
Form : Powder
Bio-activity : Determined by its ability to induce TF-1 cells proliferation. The ED50 for this effect is < 2 ng/mL.
AA Sequence : MSAPFSFLSNVKYNFMRIIKYEFIL NDALNQSIIRANDQYLTAAALHNLD EAVKFDMGAYKSSKDDAKITVILRI SKTQLYVTAQDEDQPVLLKEMPEIP KTITGSETNLLFFWETHGTKNYFTS VAHPNLFIATKQDYWVCLAGGPPSI TDFQILENQA
Endotoxin : Endotoxin level is less than 0.1 EU/μg of the protein, as determined by the LAL test.
Purity : > 95% (by SDS-PAGE)
Applications : SDS-PAGE
Notes : For laboratory research only, not for drug, diagnostic or other use.
Storage : Lyophilized protein should be stored at -20°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening.
Storage Buffer : PBS (pH 8.0)
Reconstitution : It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely.
Gene Name : EBI3 Epstein-Barr virus induced 3 [ Homo sapiens ]
Official Symbol : EBI3
Synonyms : EBI3; Epstein-Barr virus induced 3; interleukin-27 subunit beta; IL27 subunit; IL35 subunit; cytokine receptor; IL-27 subunit beta; EBV-induced gene 3 protein; Epstein-Barr virus induced gene 3; epstein-Barr virus-induced gene 3 protein; IL27B; IL-27B;
Gene ID : 10148
mRNA Refseq : NM_005755
Protein Refseq : NP_005746
MIM : 605816
UniProt ID : Q14213

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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