Recombinant Dendroaspis Angusticeps FAS2 Protein (1-61 aa), His-SUMO-tagged
Cat.No. : | FAS2-2125D |
Product Overview : | Recombinant Dendroaspis Angusticeps (Eastern green mamba) (Naja angusticeps) FAS2 Protein (1-61 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Protein Description: Full Length. |
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Description : | Interferes with neuromuscular transmission by inhibiting the enzyme acetylcholinesterase (AChE) present at the neuromuscular junction. It selectively binds and inhibits with a 1:1 stoichiometry the mammalian and electric fish AChE at picomolar concentrations. It is highly specific for the peripheral site of AChE and blocks the entry of acetylcholine into the active site of the enzyme (through the Met-33 residue), thereby preventing its breakdown. It has been called fasciculin since after injection into mice it causes severe, generalized and long-lasting (5-7 hours) fasciculations. |
Source : | E. coli |
Species : | Dendroaspis Angusticeps |
Tag : | His-SUMO |
Form : | Tris-based buffer,50% glycerol |
Molecular Mass : | 22.8 kDa |
Protein length : | 1-61 aa |
AA Sequence : | TMCYSHTTTSRAILTNCGENSCYRK SRRHPPKMVLGRGCGCPPGDDNLEV KCCTSPDKCNY |
Purity : | > 90% as determined by SDS-PAGE. |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Concentration : | A hardcopy of COA with reconstitution instruction is sent along with the products. |
Synonyms : | Fas-2; |
UniProt ID : | P0C1Z0 |
Synonyms : | Fas-2; |
UniProt ID : | P0C1Z0 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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