Recombinant Human AK1, GST-tagged
Cat.No. : | AK1-9511H |
Product Overview : | Recombinant Human AK1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Description : | Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 1-194a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | AK1 adenylate kinase 1 [ Homo sapiens ] |
Official Symbol : | AK1 |
Synonyms : | AK1; adenylate kinase 1; adenylate kinase isoenzyme 1; AK 1; myokinase; ATP-AMP transphosphorylase 1; |
Gene ID : | 203 |
mRNA Refseq : | NM_000476 |
Protein Refseq : | NP_000467 |
MIM : | 103000 |
UniProt ID : | P00568 |
Chromosome Location : | 9q34.1 |
Pathway : | Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of nucleotides, organism-specific biosystem; Purine metabolism, organism-specific biosystem; Purine metabolism, conserved biosystem; Synthesis and interconversion of nucleotide di- and triphosphates, organism-specific biosystem; |
Function : | ATP binding; adenylate kinase activity; nucleobase-containing compound kinase activity; nucleotide binding; transferase activity; |
Products Types
◆ Recombinant Protein | ||
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AK1-420M | Recombinant Mouse AK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
AK1-238R | Recombinant Rat AK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Ak1-561M | Recombinant Mouse Ak1 Protein, MYC/DDK-tagged | +Inquiry |
Ak1-105M | Recombinant Mouse Ak1 Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
AK1-6667C | Active Native Chicken AK1 | +Inquiry |
◆ Lysates | ||
AK1-8948HCL | Recombinant Human AK1 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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