AK3L1
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Official Full Name
adenylate kinase 3
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Overview
The protein encoded by this gene is a GTP:ATP phosphotransferase that is found in the mitochondrial matrix. Several transcript variants encoding a few different isoforms have been found for this gene. -
Synonyms
AK; adenylate kinase 3; AK6; FIX; AK3L1; AKL3L; AK3;
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | AK3L1-102H | Recombinant Human Adenylate Kinase 3-like 1, His-tagged | E.coli | His | ||
Human | AK4-3448H | Recombinant Human AK4, His-tagged | E.coli | His | ||
Human | AK3L1-3233H | Recombinant Human AK3L1 protein(Ala2-Tyr223) | Insect Cells | N/A | Ala2-Tyr223 |
- AK3L1 Related Articles
AK3L1 involved in several pathways and played different roles in them. We selected most pathways AK3L1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with AK3L1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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AK3L1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by AK3L1 itself. We selected most functions AK3L1 had, and list some proteins which have the same functions with AK3L1. You can find most of the proteins on our site.
Function | Related Protein |
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AK3L1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AK3L1 here. Most of them are supplied by our site. Hope this information will be useful for your research of AK3L1.
- Q&As
- Reviews
Q&As (14)
Ask a questionAK3L1 protein is produced through a process called translation, where the AK3L1 gene is transcribed into messenger RNA (mRNA) molecules. These mRNA molecules are then translated by ribosomes into the corresponding AK3L1 protein.
Currently, there is limited information on the use of AK3L1 protein as a biomarker. However, studies have suggested that AK3L1 expression levels could potentially be associated with certain diseases, such as cancer, and may have diagnostic or prognostic value.
Despite its potential importance in cellular energy metabolism, AK3L1 is relatively less studied compared to other proteins. Further research is needed to fully understand its functions and mechanisms of action.
AK3L1 protein is found in various tissues and organs, including the brain, heart, liver, and skeletal muscles.
AK3L1 has been reported to interact with other proteins involved in energy metabolism pathways, such as AMPK and mitochondrial proteins. These interactions suggest the involvement of AK3L1 in cellular energy regulation.
The regulation of AK3L1 protein is not well understood. It is believed that AK3L1 expression and activity can be influenced by various factors, including cellular energy status and signaling pathways involved in metabolism.
AK3L1 has been proposed as a potential target for drug development. Inhibition of AK3L1 activity has shown promise as a therapeutic strategy for certain types of cancer.
There are currently no specific inhibitors or activators of AK3L1 that have been developed for therapeutic use. However, studies have identified certain compounds that can modulate AK3L1 expression or activity, and further research is ongoing to explore their potential applications.
AK3L1 protein has been reported to interact with several other proteins involved in mitochondrial metabolism and signaling pathways. For example, it has been shown to bind to voltage-dependent anion channels (VDACs) and hexokinase, which are both involved in regulating mitochondrial function and energy metabolism.
AK3L1 protein is primarily localized in the mitochondrial matrix, which is the central compartment of mitochondria. Its presence in this compartment suggests a role in cellular energy metabolism and ATP production.
Yes, there are genetic variations and mutations observed in the AK3L1 gene. These variations could potentially affect the function or regulation of the protein, but more research is necessary to determine their significance.
Currently, there are no known genetic diseases specifically associated with AK3L1 protein mutations. However, variations in the AK3L1 gene have been identified in genome-wide association studies (GWAS), indicating potential associations with certain diseases or traits, such as cancer susceptibility and metabolic disorders.
Research suggests that AK3L1 may be involved in certain diseases, such as cancer and neurodegenerative disorders, although more studies are needed to fully understand its role in these conditions.
AK3L1 protein is highly conserved across different species, indicating its importance and functional significance. It shows high similarity in amino acid sequence and structural features among vertebrate species.
Customer Reviews (3)
Write a reviewArmed with the AK3L1 protein and the steadfast backing of the manufacturer's technical support, I am empowered to surmount any challenges that may impede my progress.
With their profound expertise and prompt assistance, I am confident that any obstacles I encounter will be swiftly overcome.
This invaluable support propels me towards scientific advancements within my field, contributing to the collective body of knowledge.
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