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Official Full Name adenylate kinase 2
Background Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the;reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2,;and 3, have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is;tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may;play a role in apoptosis. Mutations in this gene are the cause of reticular dysgenesis. Alternate splicing results in;multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1 and 2.
Synonyms AK2; adenylate kinase 2; adenylate kinase 2, mitochondrial; ATP-AMP transphosphorylase 2; adenylate kinase isoenzyme 2, mitochondrial; ADK2; AK 2
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • E.Coli or Yeast
    • HEK293T
    • Insect Cell
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human AK2-117H Recombinant Human Adenylate Kinase 2, His-tagged E.coli His
    Human AK2-1345H Recombinant Human AK2, His & GST tagged Insect Cell His/GST
    Human AK2-484H Recombinant Human AK2 Protein, GST-tagged Wheat Germ GST
    Human AK2-508HCL Recombinant Human AK2 cell lysate Insect Cell N/A
    Human AK2-685H Recombinant Human AK2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human AK2-9512H Recombinant Human AK2, GST-tagged E.coli GST
    Mouse AK2-1463M Recombinant Mouse AK2 Protein Mammalian Cell His
    Mouse Ak2-562M Recombinant Mouse Ak2 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Rat Ak2-3184R Recombinant Rat Ak2, His-tagged E.Coli or Yeast His
    Rat Ak2-511R Recombinant Rat Ak2 Protein, His-tagged E.coli His
    Rat AK2-583R Recombinant Rat AK2 Protein Mammalian Cell His
    Rhesus Macaque AK2-283R Recombinant Rhesus monkey AK2 Protein, His-tagged Mammalian Cell His
    Zebrafish AK2-11875Z Recombinant Zebrafish AK2 Mammalian Cell His

    ak2 involved in several pathways and played different roles in them. We selected most pathways ak2 participated on our site, such as Purine metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with ak2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Purine metabolism ADK; ADAL; NUDT9; APRT; PKM2; NT5C1A; ADKB; CANT1; NME2B.2; GMPS
    Metabolic pathways CYP2P7; CBR1L; MTHFD1; PCYT1AB; RPIA; TBXAS1; ADH1B; DAO.1; MOGS; PKMB

    ak2 has several biochemical functions, for example, ATP binding, adenylate kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ak2 itself. We selected most functions ak2 had, and list some proteins which have the same functions with ak2. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding ATP13A4; UCK1; CENPE; RUNX3; CIT; DDX55; STK38; ASCC3; MAP3K9; AK5L
    adenylate kinase activity AK7; AK5; AK2; AK8; AK1; AK4

    ak2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ak2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ak2.


    Yan, R; Chen, MX; et al. Glycoprotein lb alpha clustering induces macrophage-mediated platelet clearance in the liver. THROMBOSIS AND HAEMOSTASIS 113:107-117(2015).
    Alibardi, L; et al. Ultrastructural immunocytochemistry for the central region of keratin associated-beta-proteins (beta-keratins) shows the epitope is constantly expressed in reptilian epidermis. TISSUE & CELL 45:241-252(2013).

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