Recombinant Human IGFBP2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: IGFBP2-5679H
• Product Overview: IGFBP2 MS Standard C13 and N15-labeled recombinant protein (NP_000588) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is one of six similar proteins that bind insulin-like growth factors I and II (IGF-I and IGF-II). The encoded protein can be secreted into the bloodstream, where it binds IGF-I and IGF-II with high affinity, or it can remain intracellular, interacting with many different ligands. High expression levels of this protein promote the growth of several types of tumors and may be predictive of the chances of recovery of the patient. Several transcript variants, one encoding a secreted isoform and the others encoding nonsecreted isoforms, have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 35 kDa
• AA Sequence: MLPRVGCPALPLPPPPLLPLLPLLL LLLGASGGGGGARAEVLFRCPPCTP ERLAACGPPPVAPPAAVAAVAGGAR MPCAELVREPGCGCCSVCARLEGEA CGVYTPRCGQGLRCYPHPGSELPLQ ALVMGEGTCEKRRDAEYGASPEQVA DNGDDHSEGGLVENHVDSTMNMLGG GGSAGRKPLKSGMKELAVFREKVTE QHRQMGKGGKHHLGLEEPKKLRPPP ARTPCQQELDQVLERISTMRLPDER GPLEHLYSLHIPNCDKHGLYNLKQC KMSLNGQRGECWCVNPNTGKLIQGA PTIRGDPECHLFYNEQQEARGVHTQ RMQTRTRPLEQKLISEEDLAANDIL DYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: IGFBP2 insulin like growth factor binding protein 2 [ Homo sapiens (human) ]
• Official Symbol: IGFBP2
• Synonyms: IGFBP2; insulin-like growth factor binding protein 2, 36kDa; IBP2, insulin like growth factor binding protein 2 (36kD); insulin-like growth factor-binding protein 2; IBP-2; IGFBP-2; IGF-binding protein 2; IBP2; IGF-BP53
• Gene ID: 3485
• mRNA Refseq: NM_000597
• Protein Refseq: NP_000588
• MIM: 146731
• UniProt ID: P18065