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Official Full Name insulin-like growth factor binding protein 2, 36kDa
Background Inhibits IGF-mediated growth and developmental rates. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Synonyms IGFBP2; insulin-like growth factor binding protein 2, 36kDa; IBP2; IGF-BP53; insulin-like growth factor-binding protein 2; IBP-2; IGFBP-2; IGF-binding protein 2;
    • Species :
    • Bovine
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • CHO
    • E. coli
    • E.coli
    • HEK293
    • HEK293T
    • Human
    • Human Cell
    • Insect Cell
    • Mammalian Cell
    • NS0
    • NSO
    • yeast
    • Tag :
    • Fc
    • FLAG
    • His
    • GST
    • S
    • T7
    • Met
    • MYC/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human IGFBP2-25H Recombinant Human IGFBP2 protein, FLAG-tagged Mammalian cell FLAG
    Human IGFBP2-02H Recombinant Human IGFBP2 Protein, His-tagged E. coli His
    Mouse Igfbp2-1227M Recombinant Mouse Igfbp2 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Human IGFBP2-5679H Recombinant Human IGFBP2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human IGFBP2-11H Recombinant Human IGFBP2 yeast N/A
    Human IGFBP2-1388H Recombinant Human IGFBP2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human IGFBP2-29545TH Recombinant Human IGFBP2 protein Insect Cell N/A
    Human IGFBP2-477H Recombinant Human IGFBP2, Met-tagged NS0 Met
    Human IGFBP2-5049H Recombinant Human Insulin-Like Growth Factor Binding Protein 2, 36kDa Human N/A
    Human IGFBP2-824H Recombinant Human IGFBP2 protein, His & T7-tagged E.coli His/T7
    Mouse Igfbp2-1749M Recombinant Mouse Insulin-like Growth Factor Binding Protein 2 NSO N/A
    Mouse IGFBP2-8072M Recombinant Mouse IGFBP2 Protein Mammalian Cell His
    Mouse Igfbp2-825M Recombinant Mouse Igfbp2 protein, His & GST-tagged E.coli His/GST
    Mouse Igfbp2-969M Recombinant Mouse Igfbp2 Protein, Fc-tagged HEK293 Fc
    Mouse Igfbp2-970M Recombinant Mouse Igfbp2 Protein, His-tagged HEK293 His
    Rat IGFBP2-3008R Recombinant Rat IGFBP2 Protein Mammalian Cell His
    Rat Igfbp2-826R Recombinant Rat Igfbp2 protein, His & S-tagged E.coli His/S
    Cynomolgus Monkey IGFBP2-1457CCL Recombinant Cynomolgus IGFBP2 cell lysate Human Cell N/A
    Rhesus Macaque IGFBP2-1188R Recombinant Rhesus IGFBP2 Protein, His-tagged HEK293 His
    Bovine IGFBP2-1414B Recombinant Bovine Insulin-Like Growth Factor Binding Protein 2, 36kDa CHO N/A
    Chicken IGFBP2-6911C Recombinant Chicken IGFBP2 Mammalian Cell His

    igfbp2 involved in several pathways and played different roles in them. We selected most pathways igfbp2 participated on our site, such as Metabolism of proteins, Myometrial Relaxation and Contraction Pathways, Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs), which may be useful for your reference. Also, other proteins which involved in the same pathway with igfbp2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolism of proteins KLK13; EEF1D; ARSH; TPP1; MUC20; TRAPPC6A; ADAMTSL3; TFG; TOMM22; NSMCE4A
    Myometrial Relaxation and Contraction Pathways RGS7; GPR182; RGS19; RGS20; IGFBP5; MYLK2; RGS18; RAMP1; CORIN; ACTA1
    Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) IGFBP5; IGFBP1A; PAPPAB; PAPPA2; KLK13; IGFALS; IGFBP5B; IGFBP2; IGFBP1B; IGFBP4

    igfbp2 has several biochemical functions, for example, insulin-like growth factor I binding, insulin-like growth factor II binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by igfbp2 itself. We selected most functions igfbp2 had, and list some proteins which have the same functions with igfbp2. You can find most of the proteins on our site.

    Function Related Protein
    insulin-like growth factor I binding IGFBP3; IGFBP1A; IGFBP2; IGF1R; IGFBP1B; IGFBP2A; IGFBP4; IGFBP2B; IGFBP6; IGFBP5A
    insulin-like growth factor II binding IGFBP2A; IGFBP4; IGFBP1A; IGFBP5A; IGFBP5; IGFBP6B; IGFBP6A; IGFBP1B; IGFBP2B; IGFBP2
    protein binding TRPC1; CEP350; RXRA; BCR; XPO7; LCORL; NOG; SHPRH; PSMB2; NDUFA9

    igfbp2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with igfbp2 here. Most of them are supplied by our site. Hope this information will be useful for your research of igfbp2.

    INO80B; aroP; GSDMB

    Kang, Z; Yu, Y; et al. Downregulation of IGFBP2 is associated with resistance to IGF1R therapy in rhabdomyosarcoma. ONCOGENE 33:5697-5705(2014).
    Strimpakos, A; Pentheroudakis, G; et al. The Prognostic Role of Ephrin A2 and Endothelial Growth Factor Receptor Pathway Mediators in Patients With Advanced Colorectal Cancer Treated With Cetuximab. CLINICAL COLORECTAL CANCER 12:267-274(2013).

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