igfbp4

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igfbp4

Official Full Name insulin-like growth factor binding protein 4
Background This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.
Synonyms IGFBP4; insulin-like growth factor binding protein 4; BP-4; IBP4; IGFBP-4; HT29-IGFBP; insulin-like growth factor-binding protein 4; IBP-4; IGF-binding protein 4; Insulin-like growth factor-binding protein 4
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Pig
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Human Cell
    • Insect Cell
    • Mammalian Cell
    • Mammalian cells
    • Yeast
    • Tag :
    • His
    • T7
    • Met
    • MYC/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human IGFBP4-1385H Recombinant Human IGFBP4 Protein Insect Cell N/A
    Human IGFBP4-1389H Recombinant Human IGFBP4 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human IGFBP4-1734H Recombinant Human IGFBP4 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human IGFBP4-191H Recombinant Human IGFBP4, Met-tagged Mammalian cells Met
    Human IGFBP4-205H Recombinant Human IGFBP4 protein, His-tagged HEK293 His
    Human IGFBP4-2717H Recombinant Human Insulin-like Growth Factor Binding Protein 4 Yeast N/A
    Human IGFBP4-2926HCL Recombinant Human IGFBP4 cell lysate Human Cell N/A
    Human IGFBP4-47H Recombinant Human IGFBP4 protein E.coli N/A
    Human IGFBP4-5051H Recombinant Human IGFBP4 protein Insect Cell N/A
    Human IGFBP4-60H Recombinant Human IGFBP4 protein, T7/His-tagged E.coli T7/His
    Human IGFBP4-614H Recombinant Human Insulin-like Growth Factor Binding Protein 4 E.coli N/A
    Human IGFBP4-755H Recombinant Human IGFBP4 protein HEK293
    Human IGFBP4-759H Recombinant Human IGFBP4, His tagged Human Cell His
    Human IGFBP4-832H Recombinant Human IGFBP4 protein, His-tagged E.coli His
    Human IGFBP4-8H Recombinant Human IGFBP-4, Carrier Free Mammalian cells N/A
    Mouse Igfbp4-1228M Recombinant Mouse Igfbp4 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Mouse IGFBP4-2925MCL Recombinant Mouse IGFBP4 cell lysate Human Cell N/A
    Mouse Igfbp4-833M Recombinant Mouse Igfbp4 protein, His & T7-tagged E.coli His/T7
    Rat Igfbp4-1415R Recombinant Rat Insulin-Like Growth Factor Binding Protein 4 E.coli N/A
    Rat IGFBP4-3009R Recombinant Rat IGFBP4 Protein Mammalian Cell His
    Rat Igfbp4-835R Recombinant Rat Igfbp4 protein, His & T7-tagged E.coli His/T7
    Cynomolgus Monkey IGFBP4-1231CCL Recombinant Cynomolgus IGFBP4 cell lysate Human Cell N/A
    Cynomolgus Monkey IGFBP4-8819C Recombinant Cynomolgus IGFBP4, His tagged Human Cell His
    Rhesus Macaque IGFBP4-2219R Recombinant Rhesus monkey IGFBP4 Protein, His-tagged Mammalian Cell His
    Chicken IGFBP4-5924C Recombinant Chicken IGFBP4 Mammalian Cell His
    Pig IGFBP4-834P Recombinant Pig IGFBP4 protein, His & T7-tagged E.coli His/T7

    igfbp4 involved in several pathways and played different roles in them. We selected most pathways igfbp4 participated on our site, such as Metabolism of proteins, Myometrial Relaxation and Contraction Pathways, Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs), which may be useful for your reference. Also, other proteins which involved in the same pathway with igfbp4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolism of proteins SPCS3; MCFD2; CTSH; SEC23IP; TIMM22; IGFBP5B; O3far1; CPA3; DPH2; CKAP4
    Myometrial Relaxation and Contraction Pathways RGS18; RGS10; GUCA2B; RGS16; GUCA2A; ATF5; RGS17; RGS6; RGS19; CORIN
    Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) IGF2B; GZMH; KLK13; IGFBP6B; IGFBP1B; IGFBP5A; PAPPA2; IGFBP5; IGFBP2B; IGFALS
    Wnt signaling network IGFBP4; WIF1; RSPO1; ATP6AP2; CTHRC1; RYK

    igfbp4 has several biochemical functions, for example, insulin-like growth factor I binding, insulin-like growth factor II binding. Some of the functions are cooperated with other proteins, some of the functions could acted by igfbp4 itself. We selected most functions igfbp4 had, and list some proteins which have the same functions with igfbp4. You can find most of the proteins on our site.

    Function Related Protein
    insulin-like growth factor I binding IGFBP5A; IGFBP4; IGFBP2B; IGFBP5B; INSR; IGFBP6; IGFBP2; IGFBP6A; IGFBP2A; IGFBP1A
    insulin-like growth factor II binding IGFBP1B; INSR; IGFBP2; IGFBP6B; IGFBP3; IGFBP2A; IGFBP5; IGFBP6; IGFBP2B; IGFBP1A

    igfbp4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with igfbp4 here. Most of them are supplied by our site. Hope this information will be useful for your research of igfbp4.

    SUV39H1; KDM1A; q81l39_bacan

    Khsheibun, R; Paperna, T; et al. Gene Expression Profiling of the Response to Interferon Beta in Epstein-Barr-Transformed and Primary B Cells of Patients with Multiple Sclerosis. PLOS ONE 9:-(2014).
    Ivanov, VN; Ghandhi, SA; et al. Radiation response and regulation of apoptosis induced by a combination of TRAIL and CHX in cells lacking mitochondrial DNA: A role for NF-kappa B-STAT3-directed gene expression. EXPERIMENTAL CELL RESEARCH 317:1548-1566(2011).

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