Recombinant Human NTRK1 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | NTRK1-1225H |
Product Overview : | NTRK1 MS Standard C13 and N15-labeled recombinant protein (NP_001012331) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 86.7 kDa |
AA Sequence : | MLRGGRRGQLGWHSWAAGPGSLLAW LILASAGAAPCPDACCPHGSSGLRC TRDGALDSLHHLPGAENLTELYIEN QQHLQHLELRDLRGLGELRNLTIVK SGLRFVAPDAFHFTPRLSRLNLSFN ALESLSWKTVQGLSLQELVLSGNPL HCSCALRWLQRWEEEGLGGVPEQKL QCHGQGPLAHMPNASCGVPTLKVQV PNASVDVGDDVLLRCQVEGRGLEQA GWILTELEQSATVMKSGGLPSLGLT LANVTSDLNRKNLTCWAENDVGRAE VSVQVNVSFPASVQLHTAVEMHHWC IPFSVDGQPAPSLRWLFNGSVLNET SFIFTEFLEPAANETVRHGCLRLNQ PTHVNNGNYTLLAANPFGQASASIM AAFMDNPFEFNPEDPIPDTNSTSGD PVEKKDETPFGVSVAVGLAVFACLF LSTLLLVLNKCGRRNKFGINRPAVL APEDGLAMSLHFMTLGGSSLSPTEG KGSGLQGHIIENPQYFSDACVHHIK RRDIVLKWELGEGAFGKVFLAECHN LLPEQDKMLVAVKALKEASESARQD FQREAELLTMLQHQHIVRFFGVCTE GRPLLMVFEYMRHGDLNRFLRSHGP DAKLLAGGEDVAPGPLGLGQLLAVA SQVAAGMVYLAGLHFVHRDLATRNC LVGQGLVVKIGDFGMSRDIYSTDYY RVGGRTMLPIRWMPPESILYRKFTT ESDVWSFGVVLWEIFTYGKQPWYQL SNTEAIDCITQGRELERPRACPPEV YAIMRGCWQREPQQRHSIKDVHARL QALAQAPPVYLDVLGTRTRPLEQKL ISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | NTRK1 neurotrophic receptor tyrosine kinase 1 [ Homo sapiens (human) ] |
Official Symbol : | NTRK1 |
Synonyms : | NTRK1; neurotrophic tyrosine kinase, receptor, type 1; high affinity nerve growth factor receptor; MTC; TRK; TRKA; gp140trk; Oncogene TRK; tyrosine kinase receptor A; tropomyosin-related kinase A; TRK1-transforming tyrosine kinase protein; TRK1; Trk-A; p140-TrkA; DKFZp781I14186; |
Gene ID : | 4914 |
mRNA Refseq : | NM_001012331 |
Protein Refseq : | NP_001012331 |
MIM : | 191315 |
UniProt ID : | P04629 |
Products Types
◆ Recombinant Protein | ||
NTRK1-163N | Active Recombinant Human NTRK1 Protein | +Inquiry |
NTRK1-260H | Recombinant Active Human NTRK1 Protein (ECD), Fc-His-tagged(C-ter) | +Inquiry |
NTRK1-415M | Active Recombinant Mouse NTRK1 protein(Met1-Gly420), His-tagged | +Inquiry |
NTRK1-01H | Active Recombinant Human NTRK1 Protein (34-407), Animal free | +Inquiry |
NTRK1-1352R | Acitve Recombinant Rat NTRK1 protein(Met1-Pro418), hFc-tagged | +Inquiry |
◆ Lysates | ||
NTRK1-1086MCL | Recombinant Mouse NTRK1 cell lysate | +Inquiry |
NTRK1-1068RCL | Recombinant Rat NTRK1 cell lysate | +Inquiry |
NTRK1-2147HCL | Recombinant Human NTRK1 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1627 | TrkA Functional Assay Kit | +Inquiry |
Kit-1546 | U2OS TrkA Bioassay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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