Ntrk3

  • Official Full Name

    neurotrophic tyrosine kinase, receptor, type 3

  • Overview

    The family of Trk receptor tyrosine kinases consists of TrkA, TrkB and TrkC. While the sequence of these family members is highly conserved, they are activated by different neurotrophins: TrkA by NGF, TrkB by BDNF or NT4, and TrkC by NT3. TrkA regulates p
  • Synonyms

    NTRK3; neurotrophic tyrosine kinase, receptor, type 3; NT-3 growth factor receptor; TRKC; GP145-TrkC; ETV6-NTRK3 fusion; tyrosine kinase receptor C; ETS related protein-neurotrophic receptor tyrosine kinase fusion protein; gp145(trkC); AW125844; Ntrk3_tv3;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Sus scrofa (Pig)
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Human Cell
  • Insect Cell
  • Insect cells
  • Insect Cells
  • Mammalian Cell
  • Mammalian cells
  • Mouse
  • Sf9 Insect Cell
  • C
  • His
  • hFc
  • DDK
  • DDK|His
  • Fc
  • Flag
  • GST
  • His (Fc)
  • Avi
  • Myc
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NTRK3-160H Active Recombinant Human NTRK3, His-tagged HEK293 His
Human NTRK3-161H Active Recombinant Human NTRK3 Protein, His-tagged HEK293 His
Human NTRK3-160HAF488 Active Recombinant Human NTRK3 Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His
Human NTRK3-160HAF555 Active Recombinant Human NTRK3 Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His
Human NTRK3-160HAF647 Active Recombinant Human NTRK3 Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His
Human NTRK3-160HF Active Recombinant Human NTRK3 Protein, His-tagged, FITC conjugated HEK293 His
Human NTRK3-31622TH Recombinant Human NTRK3, His-tagged His
Human NTRK3-110H Recombinant Human NTRK3, Fc Chimera HEK293 Fc
Human NTRK3-497H Recombinant Human Neurotrophic Tyrosine Kinase, Receptor, Type 3 Mammalian cells N/A
Human NTRK3-31623TH Recombinant Human NTRK3 N/A
Human NTRK3-450H Recombinant Human NTRK3, His-tagged, Active Sf9 Insect Cell His
Human NTRK3-702H Recombinant Human NTRK3, GST-His Sf9 Insect Cell GST
Human NTRK3-159H Active Recombinant Human NTRK3 protein(Met1-Asp428), His&hFc-tagged HEK293 C-His&hFc
Human NTRK3-88H Recombinant Human NTRK3 protein, Flag-tagged, Biotinylated Insect Cell Flag
Human NTRK3-753H Recombinant Human NTRK3 Protein, DDK/His-tagged HEK293 DDK/His
Human NTRK3-1388H Recombinant Human NTRK3, GST-tagged E.coli GST
Human NTRK3-754H Recombinant Human NTRK3 Protein, DDK-tagged Sf9 Insect Cell DDK
Human NTRK3-2825HCL Recombinant Human NTRK3 cell lysate Human Cell N/A
Human NTRK3-4468H-B Recombinant Human NTRK3 Protein Pre-coupled Magnetic Beads HEK293
Human NTRK3-2936H Recombinant Human NTRK3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human NTRK3-5483H Recombinant Human NTRK3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human NTRK3-159HAF647 Recombinant Human NTRK3 Protein, Fc/His-tagged, Alexa Fluor 647 conjugated HEK293 Fc/His
Human NTRK3-380H Recombinant Human NTRK3 Protein, His-tagged E.coli His
Human NTRK3-159HAF488 Recombinant Human NTRK3 Protein, Fc/His-tagged, Alexa Fluor 488 conjugated HEK293 Fc/His
Human NTRK3-4468H Recombinant Human NTRK3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human NTRK3-159HAF555 Recombinant Human NTRK3 Protein, Fc/His-tagged, Alexa Fluor 555 conjugated HEK293 Fc/His
Human NTRK3-1279H Active Recombinant Human NTRK3 protein, hFc&His-tagged HEK293 hFc&His
Human NTRK3-159HF Recombinant Human NTRK3 Protein, Fc/His-tagged, FITC conjugated HEK293 Fc/His
Human NTRK3-0748H Recombinant Human NTRK3 protein, Fc-tagged HEK293 Fc
Mouse Ntrk3-908M Recombinant Mouse Neurotrophic Tyrosine Kinase, Receptor, Type 3, His-tagged Mouse His
Mouse Ntrk3-625M Recombinant Mouse Ntrk3, His-tagged Human Cell His
Mouse NTRK3-2583MCL Recombinant Mouse NTRK3 cell lysate Human Cell N/A
Mouse Ntrk3-009M Recombinant Mouse Ntrk3 Protein, His-tagged Insect Cells His
Mouse Ntrk3-035M Recombinant Mouse Ntrk3 Protein, His-tagged Insect cells His
Mouse Ntrk3-4524M Recombinant Mouse Ntrk3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat NTRK3-4104R Recombinant Rat NTRK3 Protein Mammalian Cell His
Rat NTRK3-3765R-B Recombinant Rat NTRK3 Protein Pre-coupled Magnetic Beads HEK293
Rat NTRK3-3765R Recombinant Rat NTRK3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque NTRK3-3119R Recombinant Rhesus monkey NTRK3 Protein, His-tagged Mammalian Cell His
Rhesus Macaque NTRK3-2938R Recombinant Rhesus Macaque NTRK3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque NTRK3-2938R-B Recombinant Rhesus Macaque NTRK3 Protein Pre-coupled Magnetic Beads HEK293
Sus scrofa (Pig) RFL23667SF Recombinant Full Length Pig Nt-3 Growth Factor Receptor(Ntrk3) Protein, His-Tagged E.coli expression system His
Chicken NTRK3-6724C Recombinant Chicken NTRK3 Mammalian Cell His
Kit-1632 U2OS TrkC Bioassay Kit N/A
Kit-1633 TrkC Functional Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Ntrk3 Related Articles

Ntrk3 involved in several pathways and played different roles in them. We selected most pathways Ntrk3 participated on our site, such as Neurotrophin signaling pathway, Central carbon metabolism in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with Ntrk3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Neurotrophin signaling pathwayPIK3CG;CALML3;CDC42;PRKCD;SHC3;SH2B1;MAP2K7;KIDINS220;MAPK3
Central carbon metabolism in cancerHKDC1;PIK3R5;FGFR3;HK1;FGFR2;MET;PTEN;MAP2K1;HIF1A

Ntrk3 has several biochemical functions, for example, ATP binding, ephrin receptor binding, neurotrophin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Ntrk3 itself. We selected most functions Ntrk3 had, and list some proteins which have the same functions with Ntrk3. You can find most of the proteins on our site.

Function Related Protein
ATP bindingCERK;PLK4;EK1;EPHA8;ABCC9;ACTB2;CDK16;FES;HSPA8
ephrin receptor bindingEPHA4;SIPA1L1;EFNB3B;GRB2;EFNA3B;EFNB2A;CBL;EFNA5B;CRK
neurotrophin bindingNGFR;NTRK2;NTRK1;NTRK3
neurotrophin receptor activityNTRK3;NTRK2B
p53 bindingSETD7;TAF3;AAAS;SMYD2;KDM1A;BANP;CREBBP;SIRT1;ZFP385C
protein bindingCSNK2B;PLEKHB1;FAM101A;DDC;C7orf50;SIRT1;NDEL1;ECSIT;CTDSP2
transmembrane receptor protein tyrosine kinase activityTIE1;CSF1RA;NTRK1;ERBB2;TYRO3;NPTNB;INSRB;DDR1;ERBB4

Ntrk3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Ntrk3 here. Most of them are supplied by our site. Hope this information will be useful for your research of Ntrk3.

SORT1; saicar; PKM; PTPN1; abl-tide; HSP90AB1; IRAK3

Manda, SS; Nirujogi, RS; et al. Identification and Characterization of Proteins Encoded by Chromosome 12 as Part of Chromosome-centric Human Proteome Project. JOURNAL OF PROTEOME RESEARCH 13:3166-3177(2014).
Takahashi, H; Arstikaitis, P; et al. Postsynaptic TrkC and Presynaptic PTP sigma Function as a Bidirectional Excitatory Synaptic Organizing Complex. NEURON 69:287-303(2011).
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