NTRK2 Protein

September 27-30, 2022

Boston Convention and Exhibition Center

Booth #336

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NTRK2

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NTRK2

Official Full Name neurotrophic tyrosine kinase, receptor, type 2
Background This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms NTRK2; neurotrophic tyrosine kinase, receptor, type 2; TRKB; trk-B; GP145-TrkB; BDNF/NT-3 growth factors receptor; trkB tyrosine kinase; tyrosine kinase receptor B; tropomyosin-related kinase B; BDNF-tropomyosine receptor kinase B; neurotrophic tyrosine receptor kinase type 2
    • Species :
    • Canine
    • Chicken
    • Dog
    • Human
    • Mouse
    • Mus musculus (Mouse)
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • E.coli expression system
    • HEK293
    • HEK293T
    • Human Cell
    • Insect Cell
    • Mammalian Cell
    • Mammalian cells
    • Sf9 Insect Cell
    • Tag :
    • DDK
    • His
    • Fc
    • Fc/His
    • Flag
    • GST
    • human
    • IgG1
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human NTRK2-158H Recombinant Human NTRK2, Fc-His tagged Human Cell Fc/His
    Human NTRK2-109H Recombinant Human NTRK2, Fc Chimera HEK293 Fc
    Human NTRK2-157H Recombinant Human NTRK2 protein, His-tagged HEK293 His
    Human NTRK2-159H Recombinant Human NTRK2 protein, Fc-tagged HEK293 human/IgG1/Fc
    Human NTRK2-31620TH Recombinant Human NTRK2 N/A
    Human NTRK2-31621TH Recombinant Human NTRK2, Fc-tagged Fc
    Human NTRK2-449H Recombinant Human NTRK2, GST-tagged, Active Sf9 Insect Cell GST
    Human NTRK2-496H Recombinant Human Neurotrophic Tyrosine Kinase, Receptor, Type 2 Mammalian cells N/A
    Human NTRK2-718H Recombinant Human NTRK2, GST-His Sf9 Insect Cell GST
    Human NTRK2-751H Recombinant Human NTRK2 Protein, DDK/His-tagged HEK293 DDK/His
    Human NTRK2-752H Recombinant Human NTRK2 Protein, DDK-tagged Sf9 Insect Cell DDK
    Human NTRK2-87H Recombinant Human NTRK2 protein, Flag-tagged, Biotinylated Insect Cell Flag
    Mouse Ntrk2-1353M Recombinant Mouse Ntrk2, His tagged Human Cell His
    Mouse Ntrk2-359M Recombinant Mouse Ntrk2 Protein, His-tagged Insect Cell His
    Rat NTRK2-1095R Recombinant Rat NTRK2 Protein, His-tagged HEK293 His
    Rat NTRK2-4103R Recombinant Rat NTRK2 Protein Mammalian Cell His
    Rat Ntrk2-7471R Recombinant Rat Ntrk2, Fc tagged Human Cell Fc
    Rhesus Macaque NTRK2-3118R Recombinant Rhesus monkey NTRK2 Protein, His-tagged Mammalian Cell His
    Canine NTRK2-1041C Recombinant Canine NTRK2 Protein, Fc-tagged HEK293 Fc
    Chicken NTRK2-6784C Recombinant Chicken NTRK2 Mammalian Cell His
    Human NTRK2-2683HCL Recombinant Human NTRK2 cell lysate Human Cell N/A
    Mouse NTRK2-1843MCL Recombinant Mouse NTRK2 cell lysate Human Cell N/A
    Rat NTRK2-1300RCL Recombinant Rat NTRK2 cell lysate Human Cell N/A
    Canine NTRK2-1024CCL Recombinant Canine NTRK2 cell lysate Human Cell N/A
    Dog NTRK2-1041CAF488 Recombinant Canine NTRK2 Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc
    Dog NTRK2-1041CAF555 Recombinant Canine NTRK2 Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc
    Dog NTRK2-1041CAF647 Recombinant Canine NTRK2 Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc
    Dog NTRK2-1041CF Recombinant Canine NTRK2 Protein, Fc-tagged, FITC conjugated HEK293 Fc
    Rat NTRK2-1095RAF488 Recombinant Rat NTRK2 Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His
    Rat NTRK2-1095RAF555 Recombinant Rat NTRK2 Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His
    Rat NTRK2-1095RAF647 Recombinant Rat NTRK2 Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His
    Rat NTRK2-1095RF Recombinant Rat NTRK2 Protein, His-tagged, FITC conjugated HEK293 His
    Mouse Ntrk2-1353MAF488 Recombinant Mouse Ntrk2 Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His
    Mouse Ntrk2-1353MAF555 Recombinant Mouse Ntrk2 Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His
    Mouse Ntrk2-1353MAF647 Recombinant Mouse Ntrk2 Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His
    Mouse Ntrk2-1353MF Recombinant Mouse Ntrk2 Protein, His-tagged, FITC conjugated HEK293 His
    Human NTRK2-157HAF488 Recombinant Human NTRK2 Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His
    Human NTRK2-157HAF555 Recombinant Human NTRK2 Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His
    Human NTRK2-157HAF647 Recombinant Human NTRK2 Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His
    Human NTRK2-157HF Recombinant Human NTRK2 Protein, His-tagged, FITC conjugated HEK293 His
    Human NTRK2-158HAF488 Recombinant Human NTRK2 Protein, Fc/His-tagged, Alexa Fluor 488 conjugated HEK293 Fc/His
    Human NTRK2-158HAF555 Recombinant Human NTRK2 Protein, Fc/His-tagged, Alexa Fluor 555 conjugated HEK293 Fc/His
    Human NTRK2-158HAF647 Recombinant Human NTRK2 Protein, Fc/His-tagged, Alexa Fluor 647 conjugated HEK293 Fc/His
    Human NTRK2-158HF Recombinant Human NTRK2 Protein, Fc/His-tagged, FITC conjugated HEK293 Fc/His
    Human NTRK2-3889H Recombinant Human NTRK2 protein, His-tagged E.coli His
    Rat Ntrk2-7471RAF488 Recombinant Rat Ntrk2 Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc
    Rat Ntrk2-7471RAF555 Recombinant Rat Ntrk2 Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc
    Rat Ntrk2-7471RAF647 Recombinant Rat Ntrk2 Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc
    Rat Ntrk2-7471RF Recombinant Rat Ntrk2 Protein, Fc-tagged, FITC conjugated HEK293 Fc
    Mus musculus (Mouse) RFL36710MF Recombinant Full Length Mouse Bdnf/Nt-3 Growth Factors Receptor(Ntrk2) Protein, His-Tagged E.coli expression system His
    Human NTRK2-379H Recombinant Human NTRK2 Protein, His-tagged E.coli His
    Human NTRK2-4731H Recombinant Human NTRK2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Ntrk2-4523M Recombinant Mouse Ntrk2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse Ntrk2-7290M Recombinant Mouse Ntrk2 Protein, His-tagged Insect Cell His
    Kit-1547 U2OS TrkB Bioassay Kit N/A
    Kit-1629 TrkB Functional Assay Kit N/A

    NTRK2 involved in several pathways and played different roles in them. We selected most pathways NTRK2 participated on our site, such as MAPK signaling pathway, Neurotrophin signaling pathway, Alcoholism, which may be useful for your reference. Also, other proteins which involved in the same pathway with NTRK2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway CACNA1G; HSC70; MAP2K5; FAS; GRB2B; PPM1AA; JIP1; TMEM37; NLK; MKNK2B
    Neurotrophin signaling pathway TRP53; CALM3; MAPK10; PLCG1; MAPK1; CAMK4; IRS1; MAGED1; ARHGDIG; MATK
    Alcoholism MAPK3; DRD1A; HIST1H3F; HIST2H2AA2; SHC1; HIST1H2AC; HIST2H2AA4; SLC29A1; HIST1H4D; CAMKK2

    NTRK2 has several biochemical functions, for example, ATP binding, brain-derived neurotrophic factor binding, brain-derived neurotrophic factor-activated receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NTRK2 itself. We selected most functions NTRK2 had, and list some proteins which have the same functions with NTRK2. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding CKBA; TRNT1; TK1; SPHK1; TLK1B; CDK13; CERK; HSPA14; GK5; CCT8
    brain-derived neurotrophic factor binding NTRK2
    brain-derived neurotrophic factor-activated receptor activity NTRK2
    neurotrophin binding NTRK1; NGFR; NTRK3; NTRK2
    protein homodimerization activity PDE2A; SMAD2; IZUMO3; CALCOCO2; CARD8; DPYD; ADSSL1; NR0B2; SRGAP2A; USH1G

    NTRK2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NTRK2 here. Most of them are supplied by our site. Hope this information will be useful for your research of NTRK2.

    saicar; PKM; SORT1; abl-tide; HSP90AB1; NTF4; EGFR; POLR2G; AP1B1; NMNAT1

    Pajtler, KW; Mahlow, E; et al. Neuroblastoma in dialog with its stroma: NTRK1 is a regulator of cellular cross-talk with Schwann cells. ONCOTARGET 5:11180-11192(2014).
    Wessels, JM; Wu, L; et al. The Brain-Uterus Connection: Brain Derived Neurotrophic Factor (BDNF) and Its Receptor (Ntrk2) Are Conserved in the Mammalian Uterus. PLOS ONE 9:-(2014).

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