Recombinant Human PPIA protein, His&Myc-tagged

• Cat.No.: PPIA-4080H
• Product Overview: Recombinant Human PPIA protein(P62937)(1-165aa), fused to N-terminal His tag and C-terminal Myc tag, was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Tag: His&Myc
• Form: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
  If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
• Molecular Mass: 23.0 kDa
• Protein length: 1-165aa
• AA Sequence: MVNPTVFFDIAVDGEPLGRVSFELF ADKVPKTAENFRALSTGEKGFGYKG SCFHRIIPGFMCQGGDFTRHNGTGG KSIYGEKFEDENFILKHTGPGILSM ANAGPNTNGSQFFICTAKTEWLDGK HVVFGKVKEGMNIVEAMERFGSRNG KTSKKITIADCGQLE
• Purity: Greater than 85% as determined by SDS-PAGE.
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Reconstitution: Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%.

Gene Information

• Gene Name: PPIA peptidylprolyl isomerase A (cyclophilin A) [ Homo sapiens ]
• Official Symbol: PPIA
• Synonyms: PPIA; peptidylprolyl isomerase A (cyclophilin A); peptidyl-prolyl cis-trans isomerase A; CYPA; PPIase A; rotamase A; cyclophilin; T cell cyclophilin; cyclosporin A-binding protein; CYPH; MGC12404; MGC23397; MGC117158
• Gene ID: 5478
• mRNA Refseq: NM_021130
• Protein Refseq: NP_066953
• MIM: 123840
• UniProt ID: P62937

Reviews

03/04/2022

The PPIA protein's robustness and stability have contributed significantly to the success of my experiments, enabling precise and reproducible measurements.

05/31/2020

I highly recommend the PPIA protein for a wide range of research applications.

06/16/2019

Its exceptional performance, in combination with its clear and distinct protein bands, make it an absolute must-have for researchers looking to achieve accurate and reliable results in their experiments.

Q&As

Can PPIA be used as a therapeutic target for infectious diseases?

PPIA has been studied in the context of infectious diseases, particularly in viral infections, as a potential therapeutic target.

Are there any side effects associated with drugs that target PPIA?

Some drugs targeting PPIA may have side effects, including immunosuppression, which needs to be carefully managed.

Is PPIA used in organ transplantation procedures?

Yes, PPIA has been studied in the context of organ transplantation due to its role in immune responses and immunosuppression.

Can PPIA be used as a potential drug target for neuroprotective therapies?

PPIA modulation has shown promise in neuroprotection, making it a potential drug target for neurodegenerative disorders.

Are there any drugs that target PPIA for clinical use?

Some drugs, such as cyclosporine, target PPIA for immunosuppressive purposes in transplantation and autoimmune diseases.