"TGFB1" Related Products

Expand
Expand

Recombinant Human TGFB1 Protein

Cat.No.: TGFB1-014H
Product Overview: Purified recombinant protein of Human transforming growth factor, beta 1 (TGFB1)(Ala279-Ser390) was expressed in CHO cells.
Description: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease. [provided by RefSeq, Aug 2016].
Source: CHO cell
Species: Human
Bio-activity: The ED50 is from 0.05 to 0.2 ng/ml, corresponding to a specific activity of 0.5 to 2.0 x 10^7 Units/mg.
Molecular Mass: 12.8 kDa
Endotoxin: Less than 0.1 EU/µg (<0.01 ng/µg) protein as determined by the LAL method.
Purity: > 98% as determined by Coomassie stained SDS-PAGE.
Concentration: Protein formulated and vialed at >50 µg/mL in specified buffer
Storage Buffer: 30% Acetonitrile, 0.1% TFA (trifluoroacetic acid)
Gene Name: TGFB1 transforming growth factor, beta 1 [ Homo sapiens ]
Official Symbol: TGFB1
Synonyms: TGFB1; transforming growth factor, beta 1; DPD1, TGFB; transforming growth factor beta-1; Camurati Engelmann disease; CED; TGFbeta; TGF-beta-1; TGF-beta 1 protein; latency-associated peptide; LAP; DPD1; TGFB;
Gene ID: 7040
mRNA Refseq: NM_000660
Protein Refseq: NP_000651
MIM: 190180
UniProt ID: P01137

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.