Active Recombinant Mouse Nrg1 Protein, His-tagged

• Cat.No.: NRG1-23M
• Product Overview: Recombinant mouse RG2 Protein (Ser20-Lys246) with a C-terminal 6-His tag was espressed in mouse myeloma cell line.

Specification

• Description: Broad expression in whole brain E14.5 (RPKM 2.0), CNS E14 (RPKM 1.9) and 17 other tissues.
• Source: Mammalian cells
• Species: Mouse
• Tag: His
• Form: Lyophilized
• Bio-activity: Measured in a serum-free cell proliferation assay using MCF‑7 human breast cancer cells. The ED50 for this effect is 0.9-5.4 ng/mL.
• Molecular Mass: 26 kDa
• N-terminal Sequence Analysis: Ser20
• Endotoxin: <0.10 EU per 1 μg of the protein by the LAL method.
• Purity: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
• Storage: 12 months from date of receipt, ≤ -20 centigrade as supplied.
  1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
  3 months, ≤ -20 centigrade under sterile conditions after reconstitution.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution in PBS.
• Preservative: Reconstitute at 500 μg/mL in PBS.

Gene Information

• Gene Name: Nrg1 neuregulin 1 [ Mus musculus (house mouse) ]
• Official Symbol: Nrg1
• Synonyms: ARIA; GGF2; GGFglial growth factor; Heregulin-1; HGL; HGLneu differentiation factor; HRG; HRG1; HRG1-alpha; HRG1-beta 1; HRGAneuregulin 1 type IV beta 1a; MST131; MSTP131; NDFheregulin, alpha (45kD, ERBB2 p185-activator); neuregulin 1 type IV beta 3; neuregulin 1; Neuregulin1; Neuregulin-1; NRG1; pro-neuregulin-1, membrane-bound isoform; pro-NRG1; sensory and motor neuron derived factor; SMDF
• Gene ID: 211323
• mRNA Refseq: NM_178591
• Protein Refseq: NP_848706
• UniProt ID: Q6DR99