Active Recombinant Full Length Human STK17B Protein, N-His-tagged

• Cat.No.: STK17B-66HFL
• Product Overview: N-terminal 6His-tagged, recombinant, full length, human DRAK2, expressed by baculovirus in Sf21 insect cells. Purified using immobilized metal affinity chromatography.

Specification

• Description: DRAK2, also known as Serine/Threonine Kinase 17b, enables ATP binding activity and protein serine/threonine kinase activity. It involves in intracellular signal transduction and positive regulation of fibroblast apoptotic process.
• Source: Sf21
• Species: Human
• Tag: His
• Protein length: Full Length
• Form: 1.28 mg/ml of enzyme in 50 mM Tris/HCl pH 7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
• Bio-activity: 14 U/mg, where one unit of DRAK2 activity is defined as 1 nmol phosphate incorporated into 250 μM KKRPQRRYSNVF per minute at 30 centigrade with a final ATP concentration of 100 μM.
• Molecular Mass: 46 kDa
• Purity: 81% by SDS-PAGE and Coomassie blue staining.
• Applications: Drug Discovery & Development
• Storage: 1 year at -70 centigrade.
• Handling Advice: Rapidly thaw the vial under cold water and immediately place on ice. Aliquot unused material into prechilled micro-centrifuge tubes and immediately snap-freeze the vials in liquid nitrogen prior to re-storage at -70 centigrade.
• Use/Stability: On receipt of material store at -20 centigrade. Unopened reagent is stable for a minimum of 6 months from date of shipment when stored at recommended storage temperature. Avoid repeat freeze/thaw cycles. For maximum recovery of product, centrifuge original vial prior to removing the cap.

Gene Information

• Gene Name: STK17B serine/threonine kinase 17b [ Homo sapiens (human) ]
• Official Symbol: STK17B
• Synonyms: STK17B; serine/threonine kinase 17b; DRAK2
• Gene ID: 9262
• mRNA Refseq: NM_004226.4
• Protein Refseq: NP_004217.1
• MIM: 604727
• UniProt ID: O94768