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STK39

Official Full Name

serine threonine kinase 39
Overview

SPAK (STE20/SPS1-related Pro/Ala-rich kinase) and OSR1 (oxidative stress responsive 1) are members of the GCK family serine/threonine kinases. Overexpression and in vitro studies demonstrate that SPAK is able to activate p38 MAP kinase indicating a possib
Synonyms

STK39; serine threonine kinase 39; STE20/SPS1-related proline-alanine-rich protein kinase; DCHT; SPAK; STE20/SPS1 homolog (yeast); STE20/SPS1 homolog; ste-20-related kinase; Ste20-like protein kinase; small intestine SPAK-like kinase; serine/threonine-pro;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Rat

Source

E.coli
HEK293
In Vitro Cell Free System
Insect (sf21)
Mammalian Cell
Sf9 Insect Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
His|T7
N/A
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	STK39-1490H	Active Recombinant Human STK39, His-tagged	Sf9 Insect Cell	His	Full length	Inquiry
Human	STK39-1109H	Recombinant Human Serine/Threonine Kinase 39, His-tagged	Sf9 Insect Cell	His		Inquiry
Human	STK39-29509TH	Recombinant Human STK39, His-tagged	Sf9 Insect Cell	His	545 amino acids	Inquiry
Human	STK39-1398HCL	Recombinant Human STK39 293 Cell Lysate	HEK293	N/A		Inquiry
Human	STK39-7881HF	Active Recombinant Full Length Human STK39 Protein, GST-tagged	Insect (sf21)	GST	1-545	Inquiry
Human	STK39-6825HF	Recombinant Full Length Human STK39 Protein, GST-tagged	In Vitro Cell Free System	GST	545 amino acids	Inquiry
Human	STK39-679H	Recombinant Human STK39 Protein, GST-tagged	Wheat Germ	GST	1-545 aa	Inquiry
Human	STK39-5818H	Recombinant Human STK39 Protein (Tyr63-Ser545), N-His tagged	E.coli	N-His	Tyr63-Ser545	Inquiry
Human	STK39-1464H	Recombinant Human STK39 protein, His & T7-tagged	E.coli	His/T7	Tyr63~Ser545 (Accession # Q9UEW8)	Inquiry
Rat	STK39-5794R	Recombinant Rat STK39 Protein	Mammalian Cell	His		Inquiry
Rat	STK39-5453R	Recombinant Rat STK39 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	STK39-5453R-B	Recombinant Rat STK39 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein

STK39 involved in several pathways and played different roles in them. We selected most pathways STK39 participated on our site, such as TCR signaling in naive CD4+ T cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with STK39 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
TCR signaling in naive CD4+ T cells	DBNL;SLA2;STK39

STK39 has several biochemical functions, for example, ATP binding, protein binding, protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by STK39 itself. We selected most functions STK39 had, and list some proteins which have the same functions with STK39. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	KIF4A;CSNK2A2;SMYHC2;JAK2A;PAK7;STK38;MYLK2;ABCA8;ABCG4B
protein binding	MNDA;EXOC7;SNRNP27;MMACHC;BMPR2;CEP170L;TUSC2;CLINT1;PNOC
protein kinase binding	MAPK6;PIH1D1;TRIB3;CASP9;PPP1R12B;STAT3;TP53;GOLGA2;AGAP2
protein serine/threonine kinase activity	PDK3;NEK12;PRKCI;SRPK3;SLC14A2;ROCK2;MAPKAPK5;TTBK1;SMG1
receptor signaling protein serine/threonine kinase activity	SLKA;STK25B;PANK1A;TGFB2;ACVR1;ALPK2;BMPR2B;BMPR2;SBK3

STK39 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with STK39 here. Most of them are supplied by our site. Hope this information will be useful for your research of STK39.

CAB39; CD46; CTNNB1; SLC12A6; pi3p; RHOA; ATL2; ARX