stk10

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stk10

Official Full Name serine/threonine kinase 10
Background This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway.
Synonyms STK10; serine/threonine kinase 10; serine/threonine-protein kinase 10; LOK; PRO2729; lymphocyte-oriented kinase
    • Species :
    • Human
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Sf9 Insect Cell
    • Tag :
    • GST
    • His
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human STK10-1711HCL Recombinant Human STK10 cell lysate N/A
    Human STK10-2966H Recombinant Human STK10 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human STK10-343H Recombinant Human Serine/Threonine Kinase 10, GST-tagged, Active Sf9 Insect Cell GST
    Human STK10-555H Recombinant Human Serine/Threonine Kinase 10, His-tagged Sf9 Insect Cell GST
    Human STK10-765H Recombinant Human STK10, His tagged E.coli His
    Zebrafish STK10-11354Z Recombinant Zebrafish STK10 Mammalian Cell His

    stk10 involved in several pathways and played different roles in them. We selected most pathways stk10 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with stk10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    stk10 has several biochemical functions, for example, ATP binding, identical protein binding, polo kinase kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by stk10 itself. We selected most functions stk10 had, and list some proteins which have the same functions with stk10. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding PRKCHA; PIK3CG; SPEG; DDX51; UBE2F; CARS; DNAJA2; MTPAP; TTL; HYOU1
    identical protein binding PVRL2; USP4; AGXT2L1; RASSF1; JMJD6; VPS4B; TTC32; TRADD; TRAF2; ACTN2
    polo kinase kinase activity STK10
    protein binding TSC22D4; FYN; ENTPD5; UBASH3B; DAAM1; BAX; ARMC8; IFITM1; PPP1CB; PEX6
    protein homodimerization activity NR6A1A; DLK2; KCNH2; GZMA; TBC1D22A; ACTN3; CLIC6; TSG101; PML; CHKA
    protein serine/threonine kinase activity AKT3A; PRKY; NEK12; WNK1; HIPK4; MAPKAPK5; STK32B; MELK; ACVR1L; CSNK1DA

    stk10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with stk10 here. Most of them are supplied by our site. Hope this information will be useful for your research of stk10.

    abl-tide; midostaurin

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