Recombiant Hmuan AlkB, Alkylation Repair Homolog 2, His-tagged
Cat.No. : | ALKBH2-977H |
Product Overview : | Recombinant human ALKBH2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | ALKBH2-977H |
Description : | Alpha-ketoglutarate-dependent dioxygenasealkB homolog 2, also known ALKBH2, belongs to the ALKB family. Expressed in heart, colon, liver, testis, ovary, prostate and small intestine, ALKBH2 uses iron as a cofactor and functions as a dioxygenase that catalyzes the repair of alkylated DNA and RNA containing 1-methyladenine and 3-meth-ylcytosine. ALKBH2 is functionally activated by ascorbate and requires oxygen and α-ketoglutarate for enzymatic activity. |
Formulation : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol |
Molecular Weight : | 31.4kDa (281aa), confirmed by MALDI-TOF |
Purity : | > 90% by SDS – PAGE |
Sequences of amino acids : | MGSSHHHHH HSSGLVPRGSHMDRFLVKGAQ GGLLRKQEEQ EPTGEEPAVL GGDKESTRKR PRREAPGNGG HSAGPSWRHI RAEGLDCSYT VLFGKAEADE IFQELEKEVE YFTGALARVQ VFGKWHSVPR KQATYGDAGL TYTFSGLTLS PKPWIPVLER IRDHVSGVTG QTFNFVLINR YKDGCDHIGE HRDDERELAP GSPIASVSFG ACRDFVFRHK DSRGKSPSRR VAVVRLPLAH GSLLMMNHPT NTHWYHSLPV RKKVLAPRVN LTFRKILLTK K |
concentration : | 0.5 mg/ml (determined by Bradford assay) |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles. Avoid repeated freezing and thawing cycles. |
Gene Name : | ALKBH2 alkB, alkylation repair homolog 2 (E. coli) [ Homo sapiens ] |
Synonyms : | ALKBH2;alkB, alkylation repair homolog 2 (E. coli);ABH2; FLJ99103; MGC90512; alpha-ketoglutarate-dependent dioxygenasealkB homolog 2;oxy DC1;2OG-Fe(II) oxy DC1;alkylated DNA repair protein alkB homolog 2;EC 1.14.11. |
Gene ID : | 121642 |
MIM : | 610602 |
mRNA Refseq : | NM_001001655 |
Protein Refseq : | NP_001001655 |
UniProt ID : | Q6NS38 |
Chromosome Location : | 12q24.11 |
Function : | 2-oxoglutarate-dependent dioxygenase activity;DNA-N1-methyladenine dioxygenase activity;cytosine C-5 DNA demethylase activity;damaged DNA binding;ferrous iron binding;metal ion binding;oxidoreductase activity;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen. |
Products Types
◆ Recombinant Protein | ||
Alkbh2-1600M | Recombinant Mouse Alkbh2 Protein, Myc/DDK-tagged | +Inquiry |
ALKBH2-474M | Recombinant Mouse ALKBH2 Protein, His (Fc)-Avi-tagged | +Inquiry |
ALKBH2-133R | Recombinant Rhesus Macaque ALKBH2 Protein, His (Fc)-Avi-tagged | +Inquiry |
ALKBH2-305R | Recombinant Rhesus monkey ALKBH2 Protein, His-tagged | +Inquiry |
ALKBH2-4576H | Recombinant Human ALKBH2 protein, GST-tagged | +Inquiry |
◆ Lysates | ||
ALKBH2-8902HCL | Recombinant Human ALKBH2 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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