ALKBH7
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Official Full Name
alkB, alkylation repair homolog 7 (E. coli)
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Synonyms
ALKBH7;alkB, alkylation repair homolog 7 (E. coli);21306;ENSG00000125652;ABH7;SPATA11;UNQ6002;19p13.3;MGC10974;probable alpha-ketoglutarate-dependent dioxygenase ABH7;probable alpha-ketoglutarate-dependent dioxygenase ABH7;spermatogenesis associated 11;spermatogenesis-associated protein 11;alkylated DNA repair protein alkB homolog 7;spermatogenesis cell proliferation related protein;spermatogenesis cell proliferation-related protein;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Zebrafish
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Flag
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
ALKBH7 involved in several pathways and played different roles in them. We selected most pathways ALKBH7 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ALKBH7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
ALKBH7 has several biochemical functions, for example, dioxygenase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ALKBH7 itself. We selected most functions ALKBH7 had, and list some proteins which have the same functions with ALKBH7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| dioxygenase activity | PHYHD1;ALOX8;HPDA;PTGS1;BCO2L;KDM4C;JMJD1C;ALOX5B.3;TDO2A |
| metal ion binding | RNF44;YME1L1;CYP4A14;MT1X;TENC1;FGD;ZIC6;FYN;TRPM6 |
ALKBH7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ALKBH7 here. Most of them are supplied by our site. Hope this information will be useful for your research of ALKBH7.
ESR1
- Q&As
- Reviews
Q&As (13)
Ask a questionYes, the ALKBH7 gene has been shown to be important for the proper maintenance of nervous system development and function.
The expression pattern of ALKBH7 gene showed broad, tissue specific and period specific.
Some studies have found that ALKBH7 gene is highly expressed in liver cancer cells and is closely related to the progression and prognosis of liver cancer.
Yes, some studies suggest that mutations in the ALKBH7 gene may promote the development and spread of tumors and may contribute to the development of related diseases such as neurological disorders.
The mRNA cap reader protein recognizes and binds to the 3' end of a methylated RNA molecule. Its function is to help transcription factors effectively bind to mRNA, thus promoting the normal process of protein production.
Some diseases that are known to be related to the ALKBH7 gene include liver cancer, pancreatic cancer, lung cancer, schizophrenia, and Alzheimer's disease.
At present, some inhibitors targeting ALKBH7 gene have been developed, such as plant silicates and so on.
ALKBH7 regulates RNA methylation and demethylation, and is involved in cellular processes such as RNA stability, transcription and translation.
ALKBH7 gene is highly expressed in sperm, but the expression rate of ALKBH7 gene in other tissues and cell types varies with physiological activity and different developmental stages.
ALKBH7 gene has been shown to participate in ATM/ATR signaling pathway, Wnt signaling pathway, NF-κB signaling pathway, etc.
Yes, mutations in the ALKBH7 gene are heritable.
Although the ALKBH7 gene is widely expressed in multiple tissues, it has not been found to be involved in DNA repair processes, focusing on its role in RNA stability and transcription.
Studies of the ALKBH7 gene suggest that it may be involved in some cancers and tumours, but more extensive research is needed.
Customer Reviews (4)
Write a reviewGrowth factor activity that promotes cell growth and proliferation.
Easy to use, high stability, significant effect.
It has good application performance in immunodetection, such as ELISA, Western blot, etc.
Synthesized with high efficiency and yield.
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