Recombinant Human RAC2, GST-tagged
Cat.No. : | RAC2-2148H |
Product Overview : | Recombinant Human RAC2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 1-192aa |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) [ Homo sapiens ] |
Official Symbol : | RAC2 |
Synonyms : | RAC2; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2); ras-related C3 botulinum toxin substrate 2; EN 7; p21-Rac2; small G protein; rho family, small GTP binding protein Rac2; Ras-related C3 botulinum toxin substrat |
Gene ID : | 5880 |
mRNA Refseq : | NM_002872 |
Protein Refseq : | NP_002863 |
MIM : | 602049 |
UniProt ID : | P15153 |
Chromosome Location : | 22q13.1 |
Pathway : | Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; Axon guidance, organism-specific biosystem; B cell receptor signaling pathway, organism |
Function : | GTP binding; GTPase activity; nucleotide binding; |
Products Types
◆ Lysates | ||
RAC2-526HCL | Recombinant Human RAC2 lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionSeveral small molecule inhibitors targeting RAC2 are under development for the treatment of cancer and other diseases.
Like any targeted therapy, RAC2 inhibitors may have potential side effects, which need to be carefully evaluated in clinical trials.
RAC2 interacts with various downstream effectors and signaling molecules to regulate cellular processes such as cytoskeletal dynamics and gene expression.
Yes, mutations in the RAC2 gene have been linked to primary immunodeficiency disorders, affecting the function of immune cells.
Yes, abnormal expression or activity of RAC2 has been observed in certain diseases, making it a potential biomarker for diagnostic purposes.
Customer Reviews (3)
Write a reviewRAC2 protein has shown great utility in protein electron microscopy structure analysis.
The use of RAC2 protein in such analyses provides valuable structural insights that contribute to the elucidation of ANO2's functional mechanisms and potential drug targeting sites.
By visualizing the structural features, interactions, and conformational changes of RAC2, researchers gain valuable insights into its function and potential for therapeutic interventions.
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