Recombinant Human Ras-Related C3 Botulinum Toxin Substrate 2 (Rho Family, Small GTP Binding Protein Rac2), His-tagged
Cat.No. : | RAC2-4536H |
Product Overview : | RAC2 Human Recombinant fused with 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 209 amino acids (1- 189 a.a.) and having a molecular mass of 23.3kDa. The RAC2 is purified by proprietary chromatographic techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | RAC2-4536H |
Description : | RAC2 is a small signaling G protein/GTPase which is part of the RAS superfamily of small GTP-binding proteins which regulate cell growth, actin cytoskeletal organization, cell proliferation, survival, cell cycle progression, gene transcription rgulation and the activation of protein kinases. RAC2 cycles between an active gtp-bound and inactive gdp-bound state. In active state, RAC2 binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. RAC2 is involved in the regulation of the nadph oxidase. |
Source : | Human |
Host : | Escherichia Coli. |
Form : | The RAC2 solution contains 20mM Tris-HCl buffer (pH 8.0), 20% Glycerol, 2mM EDTA, 2mM DTT and 0.1M NaCl. |
Purity : | Greater than 95.0% as determined by SDS-PAGE. |
Physical Appearance : | Sterile Filtered colorless solution. |
Amino acid sequence : | MGSSHHHHHH SSGLVPRGSH MQAIKCVVVG DGAVGKTCLL ISYTTNAFPG EYIPTVFDNY SANVMVDSKP VNLGLWDTAG QEDYDRLRPL SYPQTDVFLI CFSLVSPASY ENVRAKWFPE VRHHCPSTPI ILVGTKLDLR DDKDTIEKLK EKKLAPITYP QGLALAKEID SVKYLECSAL TQRGLKTVFD EAIRAVLCPQ PTRQQKRAC |
Storage : | RAC2 although stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
Gene Name : | RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) [ Homo sapiens ] |
Official Symbol : | RAC2 |
Synonyms : | RAC2; Gx; EN-7; HSPC022; ras-related C3 botulinum toxin substrate 2; p21-Rac2; small G protein; OTTHUMP00000197775; OTTHUMP00000197777; OTTHUMP00000197778; OTTHUMP00000197779; rho family, small GTP binding protein Rac2; Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP-binding protein Rac2) |
Gene ID : | 5880 |
mRNA Refseq : | NM_002872 |
Protein Refseq : | NP_002863 |
MIM : | 602049 |
UniProt ID : | P15153 |
Chromosome Location : | 22q13.1 |
Pathway : | Adherens junction; Axon guidance; B cell receptor signaling pathway; Chemokine signaling pathway; Colorectal cancer; Fc epsilon RI signaling pathway; Fc gamma R-mediated phagocytosis; Focal adhesion; Leukocyte transendothelial migration; MAPK signaling pathway; Natural killer cell mediated cytotoxicity; Pancreatic cancer; Pathways in cancer; Regulation of actin cytoskeleton; VEGF signaling pathway; Wnt signaling pathway; Signaling by Rho GTPases |
Function : | GTP binding; GTPase activity; nucleotide binding; protein binding |
Products Types
◆ Recombinant Protein | ||
RAC2-3587R | Recombinant Rhesus Macaque RAC2 Protein, His (Fc)-Avi-tagged | +Inquiry |
RAC2-7380M | Recombinant Mouse RAC2 Protein, His (Fc)-Avi-tagged | +Inquiry |
RAC2-4492C | Recombinant Chicken RAC2 | +Inquiry |
RAC2-3770R | Recombinant Rhesus monkey RAC2 Protein, His-tagged | +Inquiry |
RAC2-2549H | Recombinant Human RAC2 protein, His-tagged | +Inquiry |
◆ Lysates | ||
RAC2-526HCL | Recombinant Human RAC2 lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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