Recombinant Human LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae), His-tagged

• Cat.No.: LSM5-293H
• Product Overview: LSM5, 1-91aa, Human, His tag, E.coli

Specification

• Description: Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family. Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing. Recombinant human LSM5 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Source: E.coli
• Species: Human
• Tag: His-tag
• Form: Liquid. In 20mM Tris-HCl(pH 8.5) containing 10% glycerol, 0.15M NaCl, 1mM DTT
• Molecular Mass: 12.3 kDa (114aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMAANATT NPSQLLPLEL VDKCIGSRIH IVMKSDKEIV GTLLGFDDFV NMVLEDVTEF EITPEGRRIT KLDQILLNGN NITMLVPGGE GPEV
• Purity: >95% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 1mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: LSM5
• Synonyms: LSM5; LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae); U6 snRNA-associated Sm-like protein LSm5; YER146W; FLJ12710
• Gene ID: 23658
• mRNA Refseq: NM_001130710
• Protein Refseq: NP_001124182
• MIM: 607285
• UniProt ID: Q9Y4Y9
• Chromosome Location: 7p14.3
• Pathway: Deadenylation-dependent mRNA decay, organism-specific biosystem; Gene Expression, organism-specific biosystem; Lsm 1-7 complex, organism-specific biosystem; Lsm 2-8 complex, organism-specific biosystem; RNA degradation, organism-specific biosystem; RNA degradation, conserved biosystem; Spliceosome, organism-specific biosystem
• Function: RNA binding; protein binding