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LSM5

  • Official Full Name

    LSM5 homolog, U6 small nuclear RNA associated

  • Overview

    Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.
  • Synonyms

    LSM5; LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae); U6 snRNA-associated Sm-like protein LSm5; YER146W; FLJ12710;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human LSM5-293H Recombinant Human LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae), His-tagged E.coli His
Human LSM5-654H Recombinant Human LSM5, GST-tagged E.coli GST 1-91aa
Human LSM5-9172HCL Recombinant Human LSM5 293 Cell Lysate HEK293 N/A
Human LSM5-4606H Recombinant Human LSM5 Protein, GST-tagged Wheat Germ GST
Human LSM5-6654H Recombinant Human LSM5 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human LSM5-5999HF Recombinant Full Length Human LSM5 Protein, GST-tagged In Vitro Cell Free System GST 91 amino acids
Mouse LSM5-9334M Recombinant Mouse LSM5 Protein Mammalian Cell His
Mouse Lsm5-3857M Recombinant Mouse Lsm5 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse LSM5-5227M Recombinant Mouse LSM5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse LSM5-5227M-B Recombinant Mouse LSM5 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque LSM5-2585R Recombinant Rhesus monkey LSM5 Protein, His-tagged Mammalian Cell His
Rhesus Macaque LSM5-2405R Recombinant Rhesus Macaque LSM5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque LSM5-2405R-B Recombinant Rhesus Macaque LSM5 Protein Pre-coupled Magnetic Beads HEK293
Chicken LSM5-5642C Recombinant Chicken LSM5 Mammalian Cell His
Chicken LSM5-5643C Recombinant Chicken LSM5 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • LSM5 Related Articles

LSM5 involved in several pathways and played different roles in them. We selected most pathways LSM5 participated on our site, such as RNA degradation, Spliceosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with LSM5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
RNA degradationLSM5;XRN2;DnaK;TOB2;CNOT7;BTG3;PFKMB;CNOT2;PFKL
SpliceosomeSRSF2B;SRSF9;HSPA1B;PQBP1;SRSF7B;DDX39B;CCDC12;SART1;PRPF40A

LSM5 has several biochemical functions, for example, RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LSM5 itself. We selected most functions LSM5 had, and list some proteins which have the same functions with LSM5. You can find most of the proteins on our site.

Function Related Protein
RNA bindingAPOBEC2;PTBP1A;YY1;SRSF12;CLUHA;RBM27;RPL26;ZNF385D;CNOT6
protein bindingSTRN;PPM1K;MRPL48;EEF1A2;CYBB;DPYSL4;C16orf5;RAB24;FHL5

LSM5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LSM5 here. Most of them are supplied by our site. Hope this information will be useful for your research of LSM5.

SNRPF; LSM6; LSM7

Perez-Santangelo, S; Mancini, E; et al. Role for LSM genes in the regulation of circadian rhythms. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111:15166-15171(2014).
Cui, P; Zhang, SD; et al. Dynamic regulation of genome-wide pre-mRNA splicing and stress tolerance by the Sm-like protein LSm5 in Arabidopsis. GENOME BIOLOGY 15:-(2014).
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