"SERPINB8" Related Products

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Recombinant Human serpin peptidase inhibitor, clade B (ovalbumin), member 8, His-tagged

Cat.No.: SERPINB8-686H
Product Overview: SERPINB8, 1-374aa Human, His tag, E.coli
Description: The superfamily of high molecular weight serine proteinase inhibitors (serpins) regulate a diverse set of intracellular and extracellular processes such as complement activation, fibrinolysis, coagulation, cellular differentiation, tumor suppression, apoptosis, and cell migration. SERPINB8 is a member of the ov-serpin subfamily, which, relative to the archetypal serpin PI1, is characterized by a high degree of homology to chicken ovalbumin, lack of N- and C-terminal extensions, absence of a signal peptide, and a serine rather than an asparagine residue at the penultimate position. Recombinant human SERPINB8 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Source: E.coli
Species: Human
Tag: His-tag
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol, 1mM DTT
Molecular Mass: 45.2 kDa (397aa) confirmed by MALDI-TOF
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMDDLCEA NGTFAISLFK ILGEEDNSRN VFFSPMSISS ALAMVFMGAK GSTAAQMSQA LCLYKDGDIH RGFQSLLSEV NRTGTQYLLR TANRLFGEKT CDFLPDFKEY CQKFYQAELE ELSFAEDTEE CRKHINDWVA EKTEGKISEV LDAGTVDPLT KLVLVNAIYF KGKWNEQFDR KYTRGMLFKT NEEKKTVQMM FKEAKFKMGY ADEVHTQVLE LPYVEEELSM VILLPDDNTD LAVVEKALTY EKFKAWTNSE KLTKSKVQVF LPRLKLEESY DLEPFLRRLG MIDAFDEAKA DFSGMSTEKN VPLSKVAHKC FVEVNEEGTE AAAATAVVRN SRCSRMEPRF CADHPFLFFI RHHKTNCILF CGRFSSP
Purity: >95% by SDS - PAGE
Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration: 0.5 mg/ml (determined by Bradford assay)
Gene Name: SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 [ Homo sapiens ]
Official Symbol: SERPINB8
Synonyms: SERPINB8; serpin peptidase inhibitor, clade B (ovalbumin), member 8; PI8, serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 8; serpin B8; CAP2; cytoplasmic antiproteinase 2; PI-8; peptidase inhibitor 8; protease inhibitor 8 (ovalbumin type); serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 8; PI8;
Gene ID: 5271
mRNA Refseq: NM_001031848
Protein Refseq: NP_001027018
MIM: 601697
UniProt ID: P50452
Chromosome Location: 18q21.3
Function: peptidase inhibitor activity; protein binding; serine-type endopeptidase inhibitor activity; serine-type endopeptidase inhibitor activity;

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