||Recombinant full length Human GM-CSF expressed in modified human 293 cells; amino acids 18-144 , Predicted MWt 14.5kDa.
||The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13.
||Activity:The ED50 of CSF2-27473TH is typically 0.02 - 0.2 ng/ml as measured in a cell proliferation assay using the human growth factor-dependent TF-1 cell line.
||Lyophilised:It is recommended that 0.5 ml of sterile phosphate-buffered saline be added to the vial. Following reconstitution short-term storage at 4°C is recommended, and longer-term storage of aliquots at -18 to -20°C. Repeated freeze thawing is not rec
||>95% by SDS-PAGE
||Preservative: NoneConstituents: 10% Trehalose, 1% Human serum albumin
||Store at +4°C.
|Sequences of amino acids:
||APARSPSPSTQPWEHVNAIQEARRLLNLSRDTAAEMNETV EVISEMFDLQEPTCLQTRLELYKQGLRGSLTKLKGPLT MMASHYKQHCPPTPETSCATQIITFESFKENLKDFLLV IPFDCWEPVQE
||Belongs to the GM-CSF family.