Macrophage-colony stimulating factor (M-CSF, CSF-1) receptor is an integral membrane tyrosine kinase encoded by the c-fms proto-oncogene. M-CSF receptor is expressed in monocytes (macrophages and their progenitors) and drives growth and development of thi
CSF1R involved in several pathways and played different roles in them. We selected most pathways CSF1R participated on our site, such as C-MYB transcription factor network, Cytokine-cytokine receptor interaction, Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with CSF1R were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
CSF1R has several biochemical functions, for example, ATP binding, cytokine binding, macrophage colony-stimulating factor receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CSF1R itself. We selected most functions CSF1R had, and list some proteins which have the same functions with CSF1R. You can find most of the proteins on our site.
CSF1R has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CSF1R here. Most of them are supplied by our site. Hope this information will be useful for your research of CSF1R.
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Moffat, L; Rothwell, L; et al. Development and characterisation of monoclonal antibodies reactive with porcine CSF1R (CD115). DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY 47:123-128(2014).