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Official Full Name colony stimulating factor 1 (macrophage)
Background Macrophage colony-stimulating factor, or M-CSF, is a secreted cytokine which influences hemopoietic stem cells to differentiate into macrophages or other related cell types. Eukaryotic cells also produce M-CSF in order to combat intercellular viral infection. (See colony-stimulating factor.) M-CSF binds to the Colony stimulating factor 1 receptor. It may also be involved in development of the placenta.
Synonyms CSF1; colony stimulating factor 1 (macrophage); MCSF; MGC31930; macrophage colony-stimulating factor 1; CSF-1; lanimostim; OTTHUMP00000013362; OTTHUMP00000013363; OTTHUMP00000013364; OTTHUMP00000013365; macrophage colony stimulating factor; M-CSF
    • Species :
    • Bovine
    • Chicken
    • Cynomolgus
    • Human
    • Human, Cynomolgus
    • Mouse
    • Rat
    • Source :
    • Barley Grain
    • CHO
    • E.coli
    • HEK293
    • HEK293T
    • Hordeum Vulgare
    • Human
    • Human Cell
    • Mammalian Cell
    • Silkworm
    • Wheat Germ
    • Yeast
    • Tag :
    • C-Myc/DDK
    • Fc
    • GST
    • His
    • Avi
    • S
    • His-Avi
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    • Strep II
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CSF1-033E Recombinant Human CSF1 (33-190aa), Met tagged E.coli N/A
    Human CSF1-110HG GMP Recombinant Human CSF1 Protein E.coli N/A
    Human CSF1-167H Recombinant Human Colony Stimulating Factor 1 (Macrophage) HEK293 N/A
    Human CSF1-177H Recombinant Human CSF1 protein, His/S-tagged E.coli His/S
    Human CSF1-1875H Recombinant Human Colony Stimulating Factor 1 (macrophage) HEK293 N/A
    Human CSF1-1934HCL Recombinant Human CSF1 cell lysate Human Cell N/A
    Human CSF1-1962H Recombinant Human CSF1 Protein, GST-tagged Wheat Germ GST
    Human CSF1-198H Recombinant Human CSF1 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
    Human CSF1-216H Recombinant Human CSF1, StrepII-tagged Human Cell Strep II
    Human CSF1-26835TH Recombinant Human CSF1, His-tagged His
    Human CSF1-289H Recombinant Human CSF1 protein E.coli N/A
    Human CSF1-32H Recombinant Human CSF1, His-tagged Barley Grain His
    Human CSF1-3337H Recombinant Human CSF1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human CSF1-339H Recombinant Human Colony Stimulating Factor 1 (macrophage) Human N/A
    Human CSF1-357H Recombinant Human Colony Stimulating Factor 1 (macrophage) Human N/A
    Human CSF1-418H Recombinant Human CSF1 Silkworm N/A
    Human CSF1-420H Recombinant Human CSF1 Protein, His-Avi-tagged, Biotinylated HEK293 His/Avi
    Human CSF1-424H Recombinant Human CSF1 Protein, Fc-tagged HEK293 Fc
    Human CSF1-425H Recombinant Human CSF1 protein, His-tagged HEK293 His
    Human CSF1-426H Recombinant Human CSF1 Protein, His-tagged Yeast His
    Human CSF1-427H Recombinant Human CSF1 Protein HEK293 N/A
    Human CSF1-427HB Recombinant Human CSF1 protein, His-tagged, Biotinylated HEK293 His
    Human CSF1-4319H Recombinant Human CSF1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human CSF1-4448H Recombinant Human CSF1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human CSF1-5383H Recombinant Human Colony Stimulating Factor 1 (macrophage) Hordeum Vulgare N/A
    Human CSF1-565H Recombinant Human CSF1, His tagged Human Cell His
    Human CSF1-603H Recombinant Human CSF1 protein, His-Avi-tagged HEK293 His-Avi
    Human CSF1-6225H Recombinant Human CSF1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human CSF1-698H Recombinant Human CSF1 protein, His & GST-tagged E.coli His/GST
    Human CSF1-94H Human Macrophage Colony Stimulating Factor(rDNA derived) Reference standard N/A
    Human CSF1-96H Recombinant Human CSF1, His-tagged E.coli His
    Mouse CSF1-001MCL Recombinant Mouse CSF1 cell lysate Human Cell N/A
    Mouse Csf1-041E Recombinant Mouse Csf1 (33-262aa), Met tagged E.coli N/A
    Mouse Csf1-041M Recombinant Mouse Csf1 Protein HEK293
    Mouse Csf1-042M Recombinant Mouse Csf1 Protein E.coli
    Mouse Csf1-043M Recombinant Mouse Csf1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Mouse Csf1-100M Recombinant Mouse Csf1 protein E.coli N/A
    Mouse Csf1-115MG GMP Recombinant Mouse Csf1 protein, His-tagged HEK293 His
    Mouse Csf1-178M Recombinant Mouse Csf1 protein, His/S-tagged E.coli His/S
    Mouse Csf1-290M Recombinant Mouse Csf1 protein E.coli N/A
    Mouse CSF1-40M Recombinant Mouse M-CSF Yeast N/A
    Mouse CSF1-414M Recombinant Mouse Csf1, His tagged Human Cell His
    Mouse Csf1-522M Recombinant Mouse Csf1 Human Cell N/A
    Mouse Csf1-699M Recombinant Mouse Csf1 protein, His-tagged E.coli His
    Mouse Csf1-95M Recombinant Mouse Csf1 E.coli N/A
    Rat Csf1-12R Recombinant Rat Csf1 E.coli N/A
    Rat Csf1-13R Recombinant Rat Csf1 HEK293 N/A
    Rat Csf1-14R Recombinant Rat Csf1 CHO N/A
    Rat Csf1-15R Recombinant Rat Csf1 Human Cell N/A
    Rat Csf1-179R Recombinant Rat Csf1 protein, His/S-tagged E.coli His/S
    Rat Csf1-387RG GMP Recombinant Rat Csf1 protein, His-tagged HEK293 His
    Cynomolgus CSF1-339C Recombinant Cynomolgus CSF1 Protein, His-tagged HEK293 His
    Cynomolgus CSF1-340C Recombinant Cynomolgus CSF1 Protein, Fc-tagged HEK293 Fc
    Bovine CSF1-4398B Recombinant Bovine CSF1 Protein Yeast N/A
    Chicken CSF1-4112C Recombinant Chicken CSF1 Mammalian Cell His
    Chicken CSF1-4393C Recombinant Chicken CSF1 Protein Yeast N/A
    Human, Cynomolgus CSF1-565HB Recombinant Human/Cynomolgus CSF1 protein, His-tagged, Biotinylated HEK293 His

    CSF1 involved in several pathways and played different roles in them. We selected most pathways CSF1 participated on our site, such as Cytokine-cytokine receptor interaction, Cytokines and Inflammatory Response, Hematopoietic cell lineage, which may be useful for your reference. Also, other proteins which involved in the same pathway with CSF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction KDRL; GM2002; CXCR4; CXCL10; CCL21; LIF; PLEKHO2; IFN-a; CCL26; CCL22
    Cytokines and Inflammatory Response CSF1; CSF3; CSF2
    Hematopoietic cell lineage HLA-DRB3; EPO; Itgam&Itgb2; CD3E; CD3D; CD14; CD34; GYPA; IL5RA; ITGAM; CD9
    Integrins in angiogenesis CSF1R; ANGPTL3; EDIL3; MFGE8; CSF1
    Osteoclast differentiation NOX1; NCF4; TYROBP; CAMK4; SIRPB1; IKBKB; PPP3CC; TGFB1; MAPK12; PIK3R1
    PI3K-Akt signaling pathway CDC37; EFNA4; LAMC3; CSF3; CSH1; PIK3AP1; LOC608458; CSF1; SGK2; CSH2
    Rap1 signaling pathway LOC608458; RGS14; PFN4; CSF1; EFNA4; EFNA2
    Ras signaling pathway GNG3; MAP2K2; GNGT1; FGF22; MAPK8; HGF; GNG8; KLK1B4; MRAS; FGF12

    CSF1 has several biochemical functions, for example, cytokine activity, growth factor activity, macrophage colony-stimulating factor receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CSF1 itself. We selected most functions CSF1 had, and list some proteins which have the same functions with CSF1. You can find most of the proteins on our site.

    Function Related Protein
    cytokine activity IFNK; BMP4; Il1f8; OSM; AIMP1; CCL38A.5; TNFSF13B; INHBE; BMP8B; IL6
    growth factor activity FGF11A; JAG1; FGF16; HDGFRP3; LEFTY1; BMP8A; NRG1; OGN; FGF14; HBEGFA
    macrophage colony-stimulating factor receptor binding CSF1; STAP1; IL34
    protein binding NOTCH4; SLC22A3; SID4; PAPD4; KCTD9; BCS1L; JUND; DENR; PITPNM1; THY1
    protein homodimerization activity LGALS6; BCL2; HELT; TPD52; UGT1A1; KLHL7; APOBEC3G; VPS24; MCL1B; CSF1

    CSF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CSF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CSF1.


    Moffat, L; Rothwell, L; et al. Development and characterisation of monoclonal antibodies reactive with porcine CSF1R (CD115). DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY 47:123-128(2014).
    Sauter, KA; Pridans, C; et al. Pleiotropic effects of extended blockade of CSF1R signaling in adult mice. JOURNAL OF LEUKOCYTE BIOLOGY 96:265-274(2014).

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