"IMPA1" Related Products

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Recombinant Human IMPA1, His-tagged

Cat. No.: IMPA1-2824H
Product Overview: Recombinant human IMPA1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. MW = 32.3 kDa(297aa), confirmed by MALDI-TOF.
Description: IMPA1 (inositol monophosphatase1) is responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides. It plays a key role in the phosphatidylinositol signaling pathway by catalyzing the hydrolysis of inositol monophosphates. This protein has been identified as the pharmacological target for lithium action in the brain.
Source: E.coli.
Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MADPWQECMD YAVTLARQAG EVVCEAIKNE MNVMLKSSPV DLVTATDQKV EKMLISSIKE KYPSHSFIGE ESVAAGEKSI LTDNPTWIID PIDGTTNFVH RFPFVAVSIG FAVNKKIEFG VVYSCVEGKM YTARKGKGAF CNGQKLQVSQ QEDITKSLLV TELGSSRTPE TVRMVLSNME KLFCIPVHGI RSVGTAAVNM CLVATGGADA YYEMGIHCWD VAGAGIIVTE AGGVLMDVTG GPFDLMSRRV IAANNRILAE RIAKEIQVIP LQRDDED
Purity: > 95% by SDS - PAGE.
Form: Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 10% Glycerol.
Concentration: 1 mg/ml (determined by Bradford assay).
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 [ Homo sapiens ]
Synonyms: IMPA1; inositol(myo)-1(or 4)-monophosphatase 1; IMP; IMPA; inositol monophosphatase 1; IMP 1; IMPase 1; inositol-1(or 4)-monophosphatase 1; lithium-sensitive myo-inositol monophosphatase A1; EC 3.1.3.25
Gene ID: 3612
mRNA Refseq: NM_001144878
Protein Refseq: NP_001138350
MIM: 602064
UniProt ID: P29218
Chromosome Location: 8q21.13-q21.3
Pathway: Inositol phosphate metabolism; Metabolic pathways; Phosphatidylinositol signaling system
Function: hydrolase activity; identical protein binding; inositol-1(or 4)-monophosphatase activity; metal ion binding; protein homodimerization activity

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