Recombinant Human NECTIN2 Protein, Gln32-Leu360, C-His-Avi tagged, Biotinylated

• Cat.No.: NECTIN2-189H
• Product Overview: Recombinant human Nectin-2/CD112-C-His-Avi protein was developed from HEK293 and has a target region of C-His-Avi.

Specification

• Description: This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
• Source: HEK293
• Species: Human
• Tag: C-His-Avi
• Protein length: Gln32-Leu360
• Conjugation/Label: Biotin
• Form: Lyophilised
• Endotoxin: Endotoxin level was found to be less than 0.1 ng/μg (1 EU/μg).
• Notes: FOR RESEARCH USE ONLY (RUO).
• Storage: The lyophilized protein is stable for at least 1 year from date of receipt at -20 centigrade.
• Storage Buffer: Lyophilised from 0.2 μm filtered PBS solution pH 7.4. Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20 sec, 5K RPM

Gene Information

• Gene Name: NECTIN2 nectin cell adhesion molecule 2 [ Homo sapiens (human) ]
• Official Symbol: NECTIN2
• Synonyms: NECTIN2; nectin cell adhesion molecule 2; HVEB; PRR2; CD112; PVRL2; PVRR2; nectin-2; herpesvirus entry protein B; poliovirus receptor-like 2; poliovirus receptor-related 2 (herpesvirus entry mediator B)
• Gene ID: 5819
• mRNA Refseq: NM_002856
• Protein Refseq: NP_002847
• MIM: 600798
• UniProt ID: Q92692