Recombinant Human RAB5C, member RAS oncogene family, His-tagged

• Cat.No.: RAB5C-532H
• Product Overview: RAB5C, 1-216aa, Human, His tag, E.coli

Specification

• Description: Members of the Rab protein family are small GTPases of the Ras superfamily that are thought to ensure fidelity in the process of docking and/or fusion of vesicles with their correct acceptor compartment. Recombinant human RAB5C protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Source: E.coli
• Species: Human
• Tag: His-tag
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol
• Molecular Mass: 25.9 kDa (239aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMAGRGGA ARPNGPAAGN KICQFKLVLL GESAVGKSSL VLRFVKGQFH EYQESTIGAA FLTQTVCLDD TTVKFEIWDT AGQERYHSLA PMYYRGAQAA IVVYDITNTD TFARAKNWVK ELQRQASPNI VIALAGNKAD LASKRAVEFQ EAQAYADDNS LLFMETSAKT AMNVNEIFMA IAKKLPKNEP QNATGAPGRN RGVDLQENNP ASRSQCCSN
• Purity: >90% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 1mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: RAB5C RAB5C, member RAS oncogene family [ Homo sapiens ]
• Official Symbol: RAB5C
• Synonyms: RAB5C; RAB5C, member RAS oncogene family; RABL; ras-related protein Rab-5C; RAB; member of RAS oncogene family like; member of RAS oncogene family; RAB5CL; RAB5C, member of RAS oncogene family; L1880; RAB5L; MGC117217; MGC138857
• Gene ID: 5878
• mRNA Refseq: NM_001252039
• Protein Refseq: NP_001238968
• MIM: 604037
• UniProt ID: P51148
• Chromosome Location: 17q21.2
• Pathway: Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Clathrin derived vesicle budding, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Golgi Associated Vesicle Biogenesis, organism-specific biosystem; Membrane Trafficking, organism-specific biosystem
• Function: GTP binding; GTPase activity; nucleotide binding