rab10 Protein, RAB10, member RAS oncogene family


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Official Full Name RAB10, member RAS oncogene family
Background RAB10 belongs to the RAS (see HRAS; MIM 190020) superfamily of small GTPases. RAB proteins localize to exocytic and;endocytic compartments and regulate intracellular vesicle trafficking (Bao et al., 1998 (PubMed 9918381)).
Synonyms RAB10; RAB10, member RAS oncogene family; ras-related protein Rab-10; ras related GTP binding protein; GTP-binding protein RAB10; ras-related GTP-binding protein
    • Species :
    • Chicken
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • C-Myc/DDK
    • His
    • N/A
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human RAB10-005H Recombinant Human RAB10 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
    Human RAB10-7264H Recombinant Human RAB10 protein, His-tagged E.coli His
    Human RAB10-2632HCL Recombinant Human RAB10 293 Cell Lysate HEK293 N/A
    Human RAB10-2974H Recombinant Human RAB10, T7-tagged E.coli T7
    Human RAB10-31037TH Recombinant Human RAB10, T7 -tagged E.coli T7
    Human RAB10-7263H Recombinant Human RAB10, His-tagged E.coli His
    Mouse RAB10-13780M Recombinant Mouse RAB10 Protein Mammalian Cell His
    Mouse RAB10-8694M Recombinant Mouse RAB10 Protein, His-tagged E.coli His
    Chicken RAB10-2771C Recombinant Chicken RAB10 Mammalian Cell His
    Zebrafish RAB10-687Z Recombinant Zebrafish RAB10 Mammalian Cell His

    rab10 involved in several pathways and played different roles in them. We selected most pathways rab10 participated on our site, such as AMPK signaling pathway, Endocytosis, Membrane Trafficking, which may be useful for your reference. Also, other proteins which involved in the same pathway with rab10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Endocytosis VPS26B; ERBB3A; HGS; HLA-G; SMAD3A; CAV3; AP2M1B; FMNL3; SNX4; STAM2
    Membrane Trafficking PICALMB; MYO6B; SNAPIN; CNIH2; YKT6; GJB5; BLOC1S1; CLVS2; HIP1R; CX27.5
    Translocation of GLUT4 to the plasma membrane MYO1C; RALAB; STXBP3; RALAA; RAB10
    Vesicle-mediated transport GJB5; MIA3; AP1S3A; TRAPPC6A; TRAPPC10; SNAPIN; TRAPPC1; GJD3; FTH1A; AP4B1

    rab10 has several biochemical functions, for example, GDP binding, GTP binding, GTPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by rab10 itself. We selected most functions rab10 had, and list some proteins which have the same functions with rab10. You can find most of the proteins on our site.

    Function Related Protein
    GDP binding RAB28; RALB; RHOA; GNAI1; RAB21; SRP54; KRAS; RAB7A; ARF1; PIGC
    GTPase activity ARF5; IRGF1; RHOD; GFM1; MX1; RAB32A; EEF1A1B; RAB15; RAB44; ATL2
    myosin V binding RAB27A; RAB3B; RAB39B; RAB6A; RAB11B; RAB25; RAB3D; RAB10; FUS; RAB11A
    protein binding POU2AF1; PSMG1; WDR18; ZFPL1; RIN1; ZBED4; RAD23A; GTF2IRD2; CALCR; DSCAM

    rab10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with rab10 here. Most of them are supplied by our site. Hope this information will be useful for your research of rab10.

    OPTN; ganglioside_gm1; 7242199; AURKA; DOK2; EPB41; RAB8A; AP1S1; MFSD1; TRAF6; q5nfa1_fratt; MICALL1; SBBI23; ENOPH1; UL36; pi3p; 1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate

    Hoffmann, C; Finsel, I; et al. Functional analysis of novel Rab GTPases identified in the proteome of purified Legionella-containing vacuoles from macrophages. CELLULAR MICROBIOLOGY 16:1034-1052(2014).
    Babbey, CM; Bacallao, RL; et al. Rab10 associates with primary cilia and the exocyst complex in renal epithelial cells. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 299:F495-F506(2010).

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