|Official Full Name||RAB10, member RAS oncogene family|
|Background||RAB10 belongs to the RAS (see HRAS; MIM 190020) superfamily of small GTPases. RAB proteins localize to exocytic and;endocytic compartments and regulate intracellular vesicle trafficking (Bao et al., 1998 (PubMed 9918381)).|
|Synonyms||RAB10; RAB10, member RAS oncogene family; ras-related protein Rab-10; ras related GTP binding protein; GTP-binding protein RAB10; ras-related GTP-binding protein|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
rab10 involved in several pathways and played different roles in them. We selected most pathways rab10 participated on our site, such as AMPK signaling pathway, Endocytosis, Membrane Trafficking, which may be useful for your reference. Also, other proteins which involved in the same pathway with rab10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|AMPK signaling pathway||PFKM; LEPR; PRKAG1; PIK3CG; RAB8A; ADIPOQ; CPT1B; GYS2; FASN; SREBF1|
|Endocytosis||VPS26B; ERBB3A; HGS; HLA-G; SMAD3A; CAV3; AP2M1B; FMNL3; SNX4; STAM2|
|Membrane Trafficking||PICALMB; MYO6B; SNAPIN; CNIH2; YKT6; GJB5; BLOC1S1; CLVS2; HIP1R; CX27.5|
|Translocation of GLUT4 to the plasma membrane||MYO1C; RALAB; STXBP3; RALAA; RAB10|
|Vesicle-mediated transport||GJB5; MIA3; AP1S3A; TRAPPC6A; TRAPPC10; SNAPIN; TRAPPC1; GJD3; FTH1A; AP4B1|
rab10 has several biochemical functions, for example, GDP binding, GTP binding, GTPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by rab10 itself. We selected most functions rab10 had, and list some proteins which have the same functions with rab10. You can find most of the proteins on our site.
|GDP binding||RAB28; RALB; RHOA; GNAI1; RAB21; SRP54; KRAS; RAB7A; ARF1; PIGC|
|GTP binding||EEF1A1B; IFT22; NPR1; RAB3C; NRAS; TUFM; GBP4; ARHGAP5; NKIRAS1; SEPT6|
|GTPase activity||ARF5; IRGF1; RHOD; GFM1; MX1; RAB32A; EEF1A1B; RAB15; RAB44; ATL2|
|myosin V binding||RAB27A; RAB3B; RAB39B; RAB6A; RAB11B; RAB25; RAB3D; RAB10; FUS; RAB11A|
|protein binding||POU2AF1; PSMG1; WDR18; ZFPL1; RIN1; ZBED4; RAD23A; GTF2IRD2; CALCR; DSCAM|
rab10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with rab10 here. Most of them are supplied by our site. Hope this information will be useful for your research of rab10.
OPTN; ganglioside_gm1; 7242199; AURKA; DOK2; EPB41; RAB8A; AP1S1; MFSD1; TRAF6; q5nfa1_fratt; MICALL1; SBBI23; ENOPH1; UL36; pi3p; 1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate