RAB5B
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Official Full Name
RAB5B, member RAS oncogene family -
Synonyms
RAB5B;RAB5B, member RAS oncogene family;ras-related protein Rab-5B
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RAB5B-2131H | Recombinant Human RAB5B, GST-tagged | E.coli | Human | GST | 1-215aa | |
| RAB5B-12143Z | Recombinant Zebrafish RAB5B | Mammalian Cells | Zebrafish | His |
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| RAB5B-3393H | Recombinant Human RAB5B, Member RAS Oncogene Family, His-tagged | E.coli | Human | His |
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| RAB5B-4479C | Recombinant Chicken RAB5B | Mammalian Cells | Chicken | His |
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| RAB5B-523HCL | Recombinant Human RAB5B lysate | HEK293 | Human | Non |
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Involved Pathway
RAB5B involved in several pathways and played different roles in them. We selected most pathways RAB5B participated on our site, such as Ras signaling pathway,Endocytosis,Phagosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with RAB5B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Endocytosis | PIP5K1A,MET,PSD,CAV3,CCDC53,KITB,CHMP5,VTA1,MHC1UXA2,IL2RG |
| Amoebiasis | COL5A2,LAMC1,ACTN3,TGFB1,CD14,PIK3CG,COL24A1,SERPINB1C,COL4A1,IL1B2 |
| Tuberculosis | CLEC4M,MRC1,ARHGEF12,TNF,CD209A,IFNA10,IFNA21,MRC2,IFNA8,TLR9 |
| Ras signaling pathway | PLA2G2D,FGF11,FGF1,PIK3R1,FGF20,FGFR4,MAPK8,TEK,KRAS,RASGRP3 |
| Phagosome | Ctsl,HLA-A,CLEC4M,ATP6V1E2,VAMP3,CALR3B,CTSLA,MRC2,BMA1,ATPV0E2 |
Protein Function
RAB5B has several biochemical functions, for example, GDP binding,GTP binding,GTP-dependent protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RAB5B itself. We selected most functions RAB5B had, and list some proteins which have the same functions with RAB5B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | BLOC1S2A,KIF14,PNMA1,ERCC8,RPL10A,PPP3CC,RBM15B,ACPL2,NUP205,MCM7 |
| GTP binding | AGAP2,EHD1A,DRG1,REM2,RHOAC,GNA14,RAB33A,CDC42L2,SRPRB,RRAGA |
| GTP-dependent protein binding | RASGRP4,RAPGEF6,CDC42,PPIAL4A,AP3B1,RAB32,GCH1,EEA1,ARFIP2,MRAS |
| GTPase activity | GNAT3,GTPBP2,ARL8A,RAB41,RHOA,GNAI3,RAB35B,DIRAS3,RAB5C,GNB1 |
| GDP binding | RAB22A,RAB2A,RAB17,GEM,RAP2C,RAB7,RAB10,PRPS2,RALB,RAB18 |
Interacting Protein
RAB5B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RAB5B here. Most of them are supplied by our site. Hope this information will be useful for your research of RAB5B.
LRRK2;gtp;EEA1;1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate;1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate;gamma-amino-octyl-gtp;REEP5;APOA5
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References
- McAllister, JM; Legro, RS; et al. Functional genomics of PCOS: from GWAS to molecular mechanisms. TRENDS IN ENDOCRINOLOGY AND METABOLISM 26:118-124(2015).
- Segawa, T; Hazekil, K; et al. Inpp5e increases the Rab5 association and phosphatidylinositol 3-phosphate accumulation at the phagosome through an interaction with Rab20. BIOCHEMICAL JOURNAL 464:365-375(2014).
