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Recombinant Human SIX1

Cat.No. : SIX1-30869TH
Product Overview : Recombinant full length Human SIX1 with N-terminal proprietary tag, 56.98 kDa.
  • Specification
  • Gene Information
  • Related Products
Description : The protein encoded by this gene is a homeobox protein that is similar to the Drosophila sine oculis gene product. This gene is found in a cluster of related genes on chromosome 14 and is thought to be involved in limb development. Defects in this gene are a cause of autosomal dominant deafness type 23 (DFNA23) and branchiootic syndrome type 3 (BOS3).
Protein length : 284 amino acids
Molecular Weight : 56.980kDa inclusive of tags
Source : Wheat germ
Tissue specificity : Specifically expressed in skeletal muscle.
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : MSMLPSFGFTQEQVACVCEVLQQGGNLERLGRFLWSLPAC DHLHKNESVLKAKAVVAFHRGNFRELYKILESHQFSPHNH PKLQQLWLKAHYVEAEKLCGRPLGAVGKYRVRRKFPLPRT IWDGEETSYCFKEKSRGVLREWYAHNPYPSPREKRELAEA TGLTTTQVSNWFKNRRQRDRAAEAKERENTENNNSSSNKQ NQLSPLEGGKPLMSSSEEEFSPPQSPDQNSVLLLQGNMGH ARSSNYSLPGLTASQPSHGLQTHQHQLQDSLLGPLTSSLV DLGS
Sequence Similarities : Belongs to the SIX/Sine oculis homeobox family.Contains 1 homeobox DNA-binding domain.
Gene Name : SIX1 SIX homeobox 1 [ Homo sapiens ]
Official Symbol : SIX1
Synonyms : SIX1; SIX homeobox 1; deafness, autosomal dominant 23 , DFNA23, sine oculis homeobox (Drosophila) homolog 1 , sine oculis homeobox homolog 1 (Drosophila); homeobox protein SIX1;
Gene ID : 6495
mRNA Refseq : NM_005982
Protein Refseq : NP_005973
MIM : 601205
Uniprot ID : Q15475
Chromosome Location : 14q23.1
Pathway : Transcriptional misregulation in cancers, organism-specific biosystem; Transcriptional misregulation in cancers, conserved biosystem;
Function : DNA binding; protein binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription regulatory region DNA binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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