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Official Full Name SIX homeobox 2
Background This gene is a member of the vertebrate gene family which encode proteins homologous to the Drosophila sine oculis homeobox protein. The encoded protein is a transcription factor which, like other members of this gene family, may be involved in limb or eye development. [provided by RefSeq, Dec 2008]
Synonyms SIX2; SIX homeobox 2; homeobox protein SIX2; sine oculis homeobox homolog 2;
    • Species :
    • Chicken
    • Human
    • Mouse
    • Source :
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human SIX2-1824HCL Recombinant Human SIX2 293 Cell Lysate HEK293 N/A
    Mouse SIX2-15162M Recombinant Mouse SIX2 Protein Mammalian Cell His
    Chicken SIX2-3486C Recombinant Chicken SIX2 Mammalian Cell His

    six2 involved in several pathways and played different roles in them. We selected most pathways six2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with six2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    six2 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding, protein complex binding, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by six2 itself. We selected most functions six2 had, and list some proteins which have the same functions with six2. You can find most of the proteins on our site.

    Function Related Protein
    RNA polymerase II core promoter proximal region sequence-specific DNA binding HIST2H3A; ASCL1; ZSCAN21; HSF1; CEBPZ; ZIC3; MZF1; CREB3; RFX6; EBF2
    protein complex binding RAN; SIX2; VDAC1; Ctsl; HTR2A; CRIPT; CEBPA; SLC9A3R1; RXRA; AP2B1
    transcription factor activity, sequence-specific DNA binding THRAA; CSDA; FOXN2; TA; SOX4; CDX1B; SCAND3; HOXD10; MZF1; PURBA
    transcription factor binding STK4; AIP; PAX2; HDAC8; MECP2; NLRP3; HAND1; NR0B2A; GATA6; SIRT2
    transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding CEBPA; MAFA; TBX20; NR5A2; HNRNPK; ISL1; PLAG1; OTX2; GATA3; MYBL2

    six2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with six2 here. Most of them are supplied by our site. Hope this information will be useful for your research of six2.

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