Cat. No. :	KPNA2-2900H
Product Overview :	Recombinant HumanKPNA2 (1-529 aa) is expressed in E.Coli with a T7 tag at N-terminus.
Description :	Importins are involved in nuclear import and belong to a seperate class of Ran-GTP binding proteins. Importin α itself does not interact with the nuclear pore complex but functions as an adaptor that binds importin β. It is required to mediate binding of substrates to their receptors. Importin α binds directly to the nuclear localization signal of substrates.
Source :	E.Coli.
MW :	57862 Da.
Purity :	95%.
Formulation :	10 mM Tris. pH 8.0. 0.1% Triton X-100.0.002% NaN3.
Application :	MS. SDS.

Gene Name :	KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) [ Homo sapiens ]
Synonyms :	KPNA2; karyopherin alpha 2 (RAG cohort 1, importin alpha 1); QIP2; RCH1; IPOA1; SRP1alpha; KPNA2; karyopherin alpha 2; pendulin; RAG cohort 1; importin alpha 1; importin alpha 2 importin-alpha-P1; Karyopherin subunit alpha-2; RAG cohort protein 1
Gene ID :	3838
mRNA Refseq :	NM_002266
Protein Refseq :	NP_002257
MIM :	600685
UniProt ID :	P52292
Chromosome Location :	17q24.2
Function :	histone deacetylase binding; nuclear localization sequence binding; protein binding; protein transporter activity

Online Inquiry