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Official Full Name karyopherin alpha 1 (importin alpha 5)
Background Recombination activating proteins RAG1 and RAG2 regulate and mediate V(D)J recombination, the process by which genes for immunoglobulins and T-cell receptors are generated. Several other ubiquitously expressed proteins are thought to be recruited in the recombination process. Among these are the genes affected in severe combined immune deficiency and genes involved in ds-DNA break repair. The protein encoded by this gene interacts with RAG1 and may play a role in V(D)J recombination. Two transcript variants, one protein-coding and the other not, have been found for this gene.
Synonyms KPNA1; karyopherin alpha 1 (importin alpha 5); importin subunit alpha-1; IPOA5; NPI 1; RCH2; SRP1; SRP1-beta; importin alpha 5; importin-alpha-S1; RAG cohort protein 2; nucleoprotein interactor 1; karyopherin subunit alpha-1; recombination activating gene
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human KPNA1-1313H Recombinant Human KPNA1 protein, His & T7-tagged E.coli His/T7
    Human KPNA1-1446H Recombinant Human KPNA1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human KPNA1-31462TH Recombinant Human KPNA1 Wheat Germ N/A
    Human KPNA1-4892HCL Recombinant Human KPNA1 293 Cell Lysate HEK293 N/A
    Human KPNA1-4898H Recombinant Human KPNA1 Protein, GST-tagged Wheat Germ GST
    Human KPNA1-608H Recombinant Human KPNA1 Protein (8-538 aa), His-tagged E.coli His
    Mouse Kpna1-1278M Recombinant Mouse Kpna1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Mouse KPNA1-8797M Recombinant Mouse KPNA1 Protein Mammalian Cell His
    Rhesus Macaque KPNA1-2440R Recombinant Rhesus monkey KPNA1 Protein, His-tagged Mammalian Cell His
    Chicken KPNA1-2473C Recombinant Chicken KPNA1 Mammalian Cell His

    kpna1 involved in several pathways and played different roles in them. We selected most pathways kpna1 participated on our site, such as Influenza A, which may be useful for your reference. Also, other proteins which involved in the same pathway with kpna1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Influenza A IFNAR2; NXF1; Ccl12; STAT2; STAT1; MAPK12; IFNGR1; DDX39B; MAP2K4; XPO1

    kpna1 has several biochemical functions, for example, nuclear localization sequence binding, protein binding, protein transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by kpna1 itself. We selected most functions kpna1 had, and list some proteins which have the same functions with kpna1. You can find most of the proteins on our site.

    Function Related Protein
    nuclear localization sequence binding NUP214; NFKBIA; IPO5; TNPO3; IPO4; KPNA7; BRAP; KPNB3; RANBP6; KPNA2
    protein binding TRAM1; KCNJ6; RHEB; TRIM50; AIFM1; CRKL; THRAA; DACT2; TRIP10; CAMLG
    protein transporter activity AP2A2; AP1G1; TIMM9; PGAP2; CALCR; SNUPN; KPNA2; ZFYVE16; RAMP1; AP2B1

    kpna1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with kpna1 here. Most of them are supplied by our site. Hope this information will be useful for your research of kpna1.

    ANP32B; TAF9; NUP50; USP1; CLK4; EBNA1

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