Recombinant Human KLK5 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: KLK5-5870H
• Product Overview: KLK5 MS Standard C13 and N15-labeled recombinant protein (NP_001070959) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 32 kDa
• AA Sequence: MATARPPWMWVLCALITALLLGVTE HVLANNDVSCDHPSNTVPSGSNQDL GAGAGEDARSDDSSSRIINGSDCDM HTQPWQAALLLRPNQLYCGAVLVHP QWLLTAAHCRKKVFRVRLGHYSLSP VYESGQQMFQGVKSIPHPGYSHPGH SNDLMLIKLNRRIRPTKDVRPINVS SHCPSAGTKCLVSGWGTTKSPQVHF PKVLQCLNISVLSQKRCEDAYPRQI DDTMFCAGDKAGRDSCQGDSGGPVV CNGSLQGLVSWGDYPCARPNRPGVY TNLCKFTKWIQETIQANSTRTRPLE QKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: KLK5 kallikrein-related peptidase 5 [ Homo sapiens (human) ]
• Official Symbol: KLK5
• Synonyms: KLK5; kallikrein-related peptidase 5; kallikrein 5; kallikrein-5; KLK L2; SCTE; kallikrein-like protein 2; stratum corneum tryptic enzyme; KLKL2; KLK-L2
• Gene ID: 25818
• mRNA Refseq: NM_001077491
• Protein Refseq: NP_001070959
• MIM: 605643
• UniProt ID: Q9Y337