Recombinant Human KLK5 Protein, GST-tagged

• Cat.No.: KLK5-4934H
• Product Overview: Human KLK5 full-length ORF ( NP_036559.1, 1 a.a. - 293 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 58.4 kDa
• AA Sequence: MATARPPWMWVLCALITALLLGVTE HVLANNDVSCDHPSNTVPSGSNQDL GAGAGEDARSDDSSSRIINGSDCDM HTQPWQAALLLRPNQLYCGAVLVHP QWLLTAAHCRKKVFRVRLGHYSLSP VYESGQQMFQGVKSIPHPGYSHPGH SNDLMLIKLNRRIRPTKDVRPINVS SHCPSAGTKCLVSGWGTTKSPQVHF PKVLQCLNISVLSQKRCEDAYPRQI DDTMFCAGDKAGRDSCQGDSGGPVV CNGSLQGLVSWGDYPCARPNRPGVY TNLCKFTKWIQETIQANS
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: KLK5 kallikrein-related peptidase 5 [ Homo sapiens ]
• Official Symbol: KLK5
• Synonyms: KLK5; kallikrein-related peptidase 5; kallikrein 5; kallikrein-5; KLK L2; SCTE; kallikrein-like protein 2; stratum corneum tryptic enzyme; KLKL2; KLK-L2
• Gene ID: 25818
• mRNA Refseq: NM_001077491
• Protein Refseq: NP_001070959
• MIM: 605643
• UniProt ID: Q9Y337