klk6

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klk6

Official Full Name kallikrein-related peptidase 6
Background Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimers disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Synonyms KLK6; kallikrein-related peptidase 6; hK6; Bssp; Klk7; SP59; PRSS9; PRSS18; kallikrein-6; zyme; neurosin; protease M; serine protease 9; serine protease 18;
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Mammalian Cell
    • NS0
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human KLK6-1742H Recombinant Human KLK6 Protein, His-tagged NS0 His
    Human KLK6-9483H Recombinant Human KLK6 Protein, His-tagged E.coli His
    Human KLK6-1559HCL Recombinant Human KLK6 cell lysate Human Cell N/A
    Human KLK6-26891TH Recombinant Human KLK6 E.coli N/A
    Human klk6-3928H Recombinant Human KLK6, His-tagged HEK293 His
    Human KLK6-3929H Recombinant Human KLK6 Human Cell N/A
    Human KLK6-4932H Recombinant Human KLK6 Protein, GST-tagged Wheat Germ GST
    Human KLK6-605H Recombinant Human KLK6 Mammalian Cell His
    Human KLK6-690H Recombinant Human KLK6 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human KLK6-800H Recombinant Human KLK6 protein, His & GST-tagged E.coli His/GST
    Mouse Klk6-801M Recombinant Mouse Klk6 protein, His & GST-tagged E.coli His/GST
    Rat Klk6-802R Recombinant Rat Klk6 protein, His & GST-tagged E.coli His/GST
    Rhesus Macaque KLK6-2434R Recombinant Rhesus monkey KLK6 Protein, His-tagged Mammalian Cell His

    klk6 involved in several pathways and played different roles in them. We selected most pathways klk6 participated on our site, such as Alpha-synuclein signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with klk6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Alpha-synuclein signaling PARK7; TOR1A; FKBP1A; KLK6; STUB1; BLK; CSNK2A1

    klk6 has several biochemical functions, for example, protein binding, serine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by klk6 itself. We selected most functions klk6 had, and list some proteins which have the same functions with klk6. You can find most of the proteins on our site.

    Function Related Protein
    protein binding TNF; PDE4DIP; PXMP2; CRK; PRKCQ; RBFA; TSPAN12; TEX19.1; TOP1; SMG9
    serine-type endopeptidase activity GZMH; LONP1; F12; PRSS37; EGFBP2; GZMM; PLG; MCPT2; ST14; PRSS50

    klk6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with klk6 here. Most of them are supplied by our site. Hope this information will be useful for your research of klk6.

    pheserargamc; COL1A1; COL4A1; COL1A2; FGA; FGB; APP; COL4A2; COL4A5; CSN1S1; COL4A4; COL4A3; COL4A6

    Ott, C; Ainciburu, M; et al. Development of monoclonal antibodies to human kallikrein-related peptidase 6 (KLK6) and their use in an immunofluorometric assay for free KLK6. BIOLOGICAL CHEMISTRY 395:1119-1126(2014).
    Sotiropoulou, G; Pampalakis, G; et al. Development and immunochemical evaluation of a novel chicken IgY antibody specific for KLK6. CHEMISTRY CENTRAL JOURNAL 6:-(2012).

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