klk2

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klk2

Official Full Name kallikrein-related peptidase 2
Background This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Jan 2012]
Synonyms KLK2; kallikrein-related peptidase 2; hK2; hGK-1; KLK2A2; kallikrein-2; tissue kallikrein-2; glandular kallikrein 2; glandular kallikrein-1; kallikrein 2, prostatic;
    • Species :
    • Human
    • Source :
    • E.coli
    • HEK293
    • NS0
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human KLK2-122H Recombinant Human KLK2, His-tagged HEK293 His
    Human KLK2-152H Recombinant Human KLK2 protein, His-tagged NS0 His
    Human KLK2-153H Recombinant Human KLK2 protein, GST-tagged Wheat Germ GST
    Human KLK2-221H Recombinant Human kallikrein-related peptidase 2, His-tagged E.coli His
    Human KLK2-947HCL Recombinant Human KLK2 cell lysate N/A

    klk2 involved in several pathways and played different roles in them. We selected most pathways klk2 participated on our site, such as Renin-angiotensin system, Endocrine and other factor-regulated calcium reabsorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with klk2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Renin-angiotensin system KLK1B22; AGTR1B; LNPEP; MME; Ren1; KLK1B26; CTSA; NLN; AGTR1A; KLK1B24
    Endocrine and other factor-regulated calcium reabsorption GNAS; PLCB4; ATP2B1; ATP1B1; ATP1A4; GNAQ; KLK1B5; VDR; PRKCB; KLK1B8

    klk2 has several biochemical functions, for example, serine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by klk2 itself. We selected most functions klk2 had, and list some proteins which have the same functions with klk2. You can find most of the proteins on our site.

    Function Related Protein
    serine-type endopeptidase activity GZMB; TPP1; PRSS59.2; DPP4; PRSS41; KLK1B22; CELA3A; PIK3IP1; PRSS48; PRSS2

    klk2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with klk2 here. Most of them are supplied by our site. Hope this information will be useful for your research of klk2.

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