klk4

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klk4

Official Full Name kallikrein-related peptidase 4
Background Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In some tissues its expression is hormonally regulated. The expression pattern of a similar mouse protein in murine developing teeth supports a role for the protein in the degradation of enamel proteins. Alternate splice variants for this gene have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Synonyms KLK4; kallikrein-related peptidase 4; ARM1; EMSP; PSTS; AI2A1; EMSP1; KLK-L1; PRSS17; kallikrein; kallikrein-4; prostase; serine protease 17; kallikrein-like protein 1; androgen-regulated message 1; enamel matrix serine protease 1; enamel matrix serine proteinase 1; ESMP1
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • Human
    • Human Cell
    • Human Plasma
    • Mammalian cells
    • Sprague-Dawley Rat Plasma
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human KLK4-1169H Recombinant Human KLK4, His tagged Human Cell His
    Human KLK4-1358H Recombinant Human Kallikrein-Related Peptidase 4 Human N/A
    Human KLK4-2044HCL Recombinant Human KLK4 cell lysate Human Cell N/A
    Human KLK4-238H Native Human Kallikrein Human Plasma N/A
    Human KLK4-4936H Recombinant Human KLK4 Protein, GST-tagged Wheat Germ GST
    Human KLK4-555H Recombinant Human KLK4 Protein, His-tagged Mammalian cells His
    Human KLK4-685H Recombinant Human KLK4 Protein, His-tagged E.coli His
    Mouse Klk4-686M Recombinant Mouse Klk4 Protein, His/GST-tagged E.coli His/GST
    Rat KLK4-239R Native Rat Kallikrein Sprague-Dawley Rat Plasma N/A
    Rat Klk4-687R Recombinant Rat Klk4 Protein, His-tagged E.coli His

    klk4 involved in several pathways and played different roles in them. We selected most pathways klk4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with klk4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    klk4 has several biochemical functions, for example, metal ion binding, protein binding, serine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by klk4 itself. We selected most functions klk4 had, and list some proteins which have the same functions with klk4. You can find most of the proteins on our site.

    Function Related Protein
    metal ion binding AOX3L1; PRKCHA; ENDOU2; KARS; ZFP346; ADNP2A; ACY3; KEX2; COL18A1; EGR2
    protein binding CXXC5; NMI; MAPRE3; CD36; MED28; CIAO1; EYA1; RAB35; SF3B3; CSK
    serine-type endopeptidase activity MCPT2; APEH; PRSS41; HTRA3; PRSS58; MASP2; GZMH; PRSS27; MMP8; PCSK9
    serine-type peptidase activity KLK12; TMPRSS7; SEC11C; TMPRSS4A; PRSS28; TPP1; PROCA; PRSS3; KLK1B5; PARLA

    klk4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with klk4 here. Most of them are supplied by our site. Hope this information will be useful for your research of klk4.

    TYRO3

    Yang, F; Chen, YZ; et al. Stromal TGF-beta signaling induces AR activation in prostate cancer. ONCOTARGET 5:10854-10869(2014).
    Debelec-Butuner, B; Alapinar, C; et al. Inflammation-Mediated Abrogation of Androgen Signaling: An In Vitro Model of Prostate Cell Inflammation. MOLECULAR CARCINOGENESIS 53:85-97(2014).

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