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Recombinant Human TLR2 Protein, MYC/DDK-tagged

Cat.No. : TLR2-1106H
Product Overview : Recombinant human TLR2 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.
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  • Gene Information
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Description : The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This protein is a cell-surface protein that can form heterodimers with other TLR family members to recognize conserved molecules derived from microorganisms known as pathogen-associated molecular patterns (PAMPs). Activation of TLRs by PAMPs leads to an up-regulation of signaling pathways to modulate the host's inflammatory response. This gene is also thought to promote apoptosis in response to bacterial lipoproteins. This gene has been implicated in the pathogenesis of several autoimmune diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016].
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Molecular Mass : 89.7 kDa
Purity : >50 ug/mL as determined by microplate BCA method
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : TLR2 toll-like receptor 2 [ Homo sapiens ]
Official Symbol : TLR2
Synonyms : CD282; TIL4
Gene ID : 7097
mRNA Refseq : NM_003264
Protein Refseq : NP_003255
MIM : 603028
UniProt ID : O60603

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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